Global tuberculosis incidence has declined marginally over the past decade, and
tuberculosis remains out of control in several parts of the world including Africa and Asia …

Little is known about the impact of comorbidities on multidrug resistant (MDR) and
extensively drug resistant (XDR) tuberculosis (TB) treatment outcomes. We aimed to …

Background The emergence of programmatically incurable tuberculosis threatens to
destabilise control efforts. The aim of this study was to collect prospective patient-level data …

Background Tuberculosis (TB)-associated mortality in South Africa remains high. This
review aimed to systematically assess risk factors associated with death during TB treatment …

Tuberculosis, disease caused by Mycobacterium tuberculosis, is currently the leading cause
of death by a single infectious agent worldwide. Early, rapid and accurate identification of M …

Background The emergence of resistance to anti-tuberculosis drugs is a serious and
growing threat to public health. Next-generation sequencing is rapidly gaining traction as a …

Background The burden of drug resistant tuberculosis in Africa is largely driven by the
emergence and spread of multidrug resistant (MDR) and extensively drug resistant (XDR) …

Background: The current study is conducted with the aim to the fill the gap of information
regarding treatment outcomes and variables associated with unsuccessful outcome among …

Background Ethionamide is used to treat multidrug-resistant tuberculosis (MDR-TB). The
antimicrobial pharmacokinetics/pharmacodynamics, the contribution of ethionamide to the …

Mutations causing mono and cross-resistance among amikacin, kanamycin and
capreomycin of second-line injectable drugs (SLIDs) namely are not well understood. We …