Recent advances in on-site mass spectrometry analysis for clinical applications

X Zhou, W Zhang, Z Ouyang - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
In recent years, mass spectrometry (MS) is increasingly attracting interests for clinical
applications, which also calls for technical innovations to make a transfer of MS from …

Mass spectrometry-based proteomics as an emerging tool in clinical laboratories

AG Birhanu - Clinical Proteomics, 2023 - Springer
Mass spectrometry (MS)-based proteomics have been increasingly implemented in various
disciplines of laboratory medicine to identify and quantify biomolecules in a variety of …

Updated MS²PIP web server supports cutting-edge proteomics applications

A Declercq, R Bouwmeester, C Chiva… - Nucleic Acids …, 2023 - academic.oup.com
Interest in the use of machine learning for peptide fragmentation spectrum prediction has
been strongly on the rise over the past years, especially for applications in challenging …

Comprehending COVID-19 diagnostic tests and greenness assessment of its reported detection methods

M El-Maghrabey, G Magdy, HM Hashem… - TrAC Trends in …, 2023 - Elsevier
Abstract In 2020, World Health Organization declared a pandemic due to acute respiratory
syndrome coronavirus (SARS‐CoV‐2). COVID-19 is an extremely infective disease that has …

Rapid and sensitive detection of SARS-CoV-2 infection using quantitative peptide enrichment LC-MS analysis

A Hober, KH Tran-Minh, D Foley, T McDonald… - Elife, 2021 - elifesciences.org
Reliable, robust, large-scale molecular testing for SARS-CoV-2 is essential for monitoring
the ongoing Covid-19 pandemic. We have developed a scalable analytical approach to …

Cov2MS: An Automated and Quantitative Matrix-Independent Assay for Mass Spectrometric Measurement of SARS-CoV-2 Nucleocapsid Protein

B Van Puyvelde, K Van Uytfanghe… - Analytical …, 2022 - ACS Publications
The pandemic readiness toolbox needs to be extended, targeting different biomolecules,
using orthogonal experimental set-ups. Here, we build on our Cov-MS effort using LC–MS …

A rapid and reliable liquid chromatography/mass spectrometry method for SARS-CoV-2 analysis from gargle solutions and saliva

M Kipping, D Tänzler, A Sinz - Analytical and Bioanalytical Chemistry, 2021 - Springer
We describe a rapid liquid chromatography/tandem mass spectrometry (LC-MS/MS) method
for the direct detection and quantitation of SARS-CoV-2 nucleoprotein in gargle solutions …

Advances in rapid detection of SARS-CoV-2 by mass spectrometry

TF Wong, PK So, ZP Yao - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
COVID-19 has already been lasting for more than two years and it has been severely
affecting the whole world. Still, detection of SARS-CoV-2 remains the frontline approach to …

Identification of SARS-CoV-2 proteins from nasopharyngeal swabs probed by multiple reaction monitoring Tandem Mass Spectrometry

G Pinto, A Illiano, V Ferrucci, F Quarantelli… - ACS …, 2021 - ACS Publications
Numerous reverse transcription polymerase chain reaction (RT-PCR) tests have emerged
over the past year as the gold standard for detecting millions of cases of SARS-CoV-2 …

Development of a rapid and specific MALDI-TOF mass spectrometric assay for SARS-CoV-2 detection

L Kollhoff, M Kipping, M Rauh, U Ceglarek, G Barka… - Clinical Proteomics, 2023 - Springer
We have developed a rapid and highly specific assay for detecting and monitoring SARS-
CoV-2 infections by matrix-assisted laser desorption/ionization time-of-flight mass …