Rapid evolution of an adaptive multicellular morphology of Candida auris during systemic infection

J Bing, Z Guan, T Zheng, CL Ennis, CJ Nobile… - Nature …, 2024 - nature.com
Candida auris has become a serious threat to public health. The mechanisms of how this
fungal pathogen adapts to the mammalian host are poorly understood. Here we report the …

Fission yeast Rho1p-GEFs: from polarity and cell wall synthesis to genome stability

P García, R Celador, J Pérez-Parrilla… - International Journal of …, 2022 - mdpi.com
Rho1p is a membrane-associated protein that belongs to the Rho family of small GTPases.
These proteins coordinate processes such as actin remodelling and polarised secretion to …

Elevated levels of sphingolipid MIPC in the plasma membrane disrupt the coordination of cell growth with cell wall formation in fission yeast

AH Willet, M Wos, MG Igarashi, L Ren, LA Turner… - Plos …, 2023 - journals.plos.org
Coupling cell wall expansion with cell growth is a universal challenge faced by walled
organisms. Mutations in Schizosaccharomyces pombe css1, which encodes a PM inositol …

Special Issue “The Fungal Cell Wall Integrity Pathway”

H Martín, M Molina - Journal of Fungi, 2023 - mdpi.com
Adaptation to external changes is necessary for all cell types to survive and thrive in diverse
environments. Key to these responses are the MAPK-mediated signaling pathways …

Echinocandin Drugs Induce Differential Effects in Cytokinesis Progression and Cell Integrity

N Yagüe, L Gómez-Delgado, MÁ Curto, VSD Carvalho… - Pharmaceuticals, 2021 - mdpi.com
Fission yeast contains three essential β (1, 3)-D-glucan synthases (GSs), Bgs1, Bgs3, and
Bgs4, with non-overlapping roles in cell integrity and morphogenesis. Only the bgs4+ …

Analysis of the Localization of Schizosaccharomyces pombe Glucan Synthases in the Presence of the Antifungal Agent Caspofungin

E San-Quirico, MÁ Curto, L Gómez-Delgado… - International Journal of …, 2023 - mdpi.com
In recent years, invasive fungal infections have emerged as a common source of infections
in immunosuppressed patients. All fungal cells are surrounded by a cell wall that is essential …

BEM2, a RHO GTPase Activating Protein That Regulates Morphogenesis in S. cerevisiae, Is a Downstream Effector of Fungicidal Action of Fludioxonil

A Sharma, Y Martoliya, AK Mondal - Journal of Fungi, 2022 - mdpi.com
Fludioxonil belongs to the phenylpyrrole group of fungicides with a broad antifungal
spectrum that has been widely used in agricultural practices for the past thirty years …

El exómero coordina la señalización celular con la homeostasis iónica y lipídica

E Moscoso-Romero - 2024 - digital.csic.es
El exómero es un complejo proteico tradicionalmente relacionado con el transporte de
proteínas transmembrana desde el TGN hasta la MP. Sin embargo, algunos resultados …

Echinocandin Drugs Induce Differential Effects in Cytokinesis Progression and Cell Integrity

N Yagüe González, L Gómez-Delgado, MÁ Curto… - 2021 - digital.csic.es
Fission yeast contains three essential β (1, 3)-D-glucan synthases (GSs), Bgs1, Bgs3, and
Bgs4, with non-overlapping roles in cell integrity and morphogenesis. Only the bgs4+ …

[引用][C] Special Issue “The Fungal Cell Wall Integrity Pathway”. J. Fungi 2023, 9, 293

H Martín, M Molina - 2023 - europepmc.org
Adaptation to external changes is necessary for all cell types to survive and thrive in diverse
environments. Key to these responses are the MAPK-mediated signaling pathways …