Isoflavones: anti-inflammatory benefit and possible caveats

J Yu, X Bi, B Yu, D Chen - Nutrients, 2016 - mdpi.com
Inflammation, a biological response of body tissues to harmful stimuli, is also known to be
involved in a host of diseases, such as obesity, atherosclerosis, rheumatoid arthritis, and …

Metabolism of dietary soy isoflavones to equol by human intestinal microflora–implications for health

JP Yuan, JH Wang, X Liu - Molecular nutrition & food research, 2007 - Wiley Online Library
Soy isoflavones have received considerable attention. Individuals with isoflavones‐rich diets
have significantly lower occurrences of cardiovascular disease, osteoporosis, and some …

Activation of endothelial nitric oxide synthase by dietary isoflavones: role of NO in Nrf2-mediated antioxidant gene expression

GE Mann, DJ Rowlands, FYL Li… - Cardiovascular …, 2007 - academic.oup.com
The endothelium plays a key role in the maintenance of vascular homeostasis, and
increased oxidative stress in vascular disease leads to reduced nitric oxide bioavailability …

The role of soy isoflavones in menopausal health: report of The North American Menopause Society/Wulf H. Utian Translational Science Symposium in Chicago, IL …

TB Clarkson, WH Utian, S Barnes, EB Gold… - Menopause, 2011 - journals.lww.com
Objectives: If and to what extent soy protein, soy isoflavones, and their metabolites, including
S (-)-equol, have beneficial effects on women's health is currently unclear. The North …

Natural polyphenol disposition via coupled metabolic pathways

Z Liu, M Hu - Expert opinion on drug metabolism & toxicology, 2007 - Taylor & Francis
A major challenge associated with the development of chemopreventive polyphenols is the
lack of bioavailability in vivo, which are primarily the result of coupled metabolic activities of …

Phenolic compounds: chemistry and occurrence in fruits and vegetables

C Andrés‐Lacueva, A Medina‐Remon… - Fruit and vegetable …, 2009 - Wiley Online Library
Polyphenols are the most abundant antioxidants in human diets. They are secondary
metabolites of plants. These compounds are designed with an aromatic ring carrying one or …

A phase 2 cancer chemoprevention biomarker trial of isoflavone G-2535 (genistein) in presurgical bladder cancer patients

E Messing, JR Gee, DR Saltzstein, KM Kim… - Cancer prevention …, 2012 - AACR
The soy compound genistein has been observed preclinically to inhibit bladder cancer
growth with one potential mechanism being the inhibition of epidermal growth factor …

Urolithin A gains in antiproliferative capacity by reducing the glycolytic potential via the p53/TIGAR axis in colon cancer cells

E Norden, EH Heiss - Carcinogenesis, 2019 - academic.oup.com
Polyphenols have shown promising bioactivity in experimental in vitro and in vivo models for
cancer chemoprevention. However, consumed orally, they are often transformed by gut …

Biomarkers of legume intake in human intervention and observational studies: a systematic review

PSC Sri Harsha, RA Wahab, M Garcia-Aloy… - Genes & nutrition, 2018 - Springer
There is a growing interest in assessing dietary intake more accurately across different
population groups, and biomarkers have emerged as a complementary tool to replace …

Endocrine disruptors on and in fruits and vegetables: Estimation of the potential exposure of the French population

A Lee, S Bensaada, V Lamothe, M Lacoste… - Food Chemistry, 2022 - Elsevier
Fruits and vegetables are considered to be healthy compared to fats, carbohydrates, and
meats. However, their production involves plant protection products (PPPs) or they can …