Human milk oligosaccharides as bioactive compounds in infant formula: recent advances and trends in synthetic methods

E Pérez-Escalante, S Alatorre-Santamaría… - Critical Reviews in …, 2022 - Taylor & Francis
Human milk oligosaccharides (HMO) have attracted great interest in recent years due to
their role in boosting infants and adults health. According to several in vitro, in vivo and …

L-Fucose is involved in human–gut microbiome interactions

J Kim, YS Jin, KH Kim - Applied Microbiology and Biotechnology, 2023 - Springer
L-Fucose is one of the key metabolites in human–gut microbiome interactions. It is
continuously synthesized by humans in the form of fucosylated glycans and fucosyl …

In vitro prebiotic and anti-colon cancer activities of agar-derived sugars from red seaweeds

EJ Yun, S Yu, YA Kim, JJ Liu, NJ Kang, YS Jin, KH Kim - Marine drugs, 2021 - mdpi.com
Numerous health benefits of diets containing red seaweeds or agar-derived sugar mixtures
produced by enzymatic or acid hydrolysis of agar have been reported. However, among …

Biochemical characterization of a novel α-L-fucosidase from Pedobacter sp. and its application in synthesis of 3′-fucosyllactose and 2′-fucosyllactose

R Shi, J Ma, Q Yan, S Yang, Z Fan, Z Jiang - Applied Microbiology and …, 2020 - Springer
Fucosyllactoses have gained much attention owing to their multiple functions, including
prebiotic, immune, gut, and cognition benefits. In this study, human milk oligosaccharide …

2′-Fucosyllactose production in engineered Escherichia coli with deletion of waaF and wcaJ and overexpression of FucT2

JW Lee, S Kwak, JJ Liu, EJ Yun, YS Jin - Journal of Biotechnology, 2021 - Elsevier
Fucosyllactose (2′-FL), a major oligosaccharide of human breast milk, and is currently
supplemented into infant formula. For the overproduction of 2′-FL via fucosylation of …

Biosynthesis of L-fucose and L-fuculose using engineered Saccharomyces cerevisiae

J Kim, YE Cheong, S Yu, EJ Yun, YS Jin, KH Kim - Process Biochemistry, 2023 - Elsevier
Recently, L-fucose has received considerable attention as a potential cosmetic agent and
substrate for human oligosaccharide synthesis. To date, only two methods have been …

Production of colanic acid hydrolysate and its use in the production of fucosylated oligosaccharides by engineered Saccharomyces cerevisiae

NR Han, S Yu, EJ Yun, YS Jin, KH Kim - Process Biochemistry, 2022 - Elsevier
Fucose is a rare sugar obtained from fucoidan in brown algae. However, fucoidan contains
low amounts of fucose, making the process of obtaining fucose inefficient and expensive …

Hyperglycemia alters N-glycans on colon cancer cells through increased production of activated monosaccharides

HF Loponte, IA Oliveira, BC Rodrigues… - Glycoconjugate …, 2022 - Springer
Diabetes Mellitus (DM) is both, correlated and a known risk factor for colorectal cancer
(CRC). Besides favoring the incidence of CRC, DM also accelerates its progression …