A large body of experimental evidence suggests that neuroinflammation is a key
pathological event triggering and perpetuating the neurodegenerative process associated …

While the root causes for individual neurodegenerative diseases are distinct, many shared
pathological features and mechanisms contribute to neurodegeneration across diseases …

Endothelial cells represent the first biological barrier for compounds, including
nanoparticles, administered via the intravascular route. In the case of ischemic stroke and …

Abundant clinical, epidemiological, imaging, genetic, molecular, and pathophysiological
data together indicate that there occur an unusual inflammatory reaction and a disruption of …

As alternatives to traditional per-and polyfluoroalkyl substances, perfluoroalkyl phosphonic
acids (PFPiAs) are frequently detected in aquatic environments, but the neurotoxic effects …

The gut microbial ecosystem communicates bidirectionally with the brain in what is known
as the gut-microbiome-brain axis. Bidirectional signaling occurs through several pathways …

Hydrogen sulfide (H2S), as an important endogenous signaling molecule, plays a vital role
in many physiological processes. The abnormal behaviors of hydrogen sulfide in organisms …

Centella asiatica (C. asiatica) is one of the medicinal plants that has been reported to exert
comprehensive neuroprotection in vitro and in vivo. In view of this, the present study was …

Systemic lipopolysaccharide (LPS) triggers neuroinflammation with consequent
development of behavioral and cognitive deficits. Neuroinflammation plays a crucial role in …

Alzheimer's disease (AD) is a common neurodegenerative disease in the elderly and is the
most common type of dementia. AD is mostly gradual onset, and involves slow, progressive …