Plants metabolites: possibility of natural therapeutics against the COVID-19 pandemic

FR Bhuiyan, S Howlader, T Raihan, M Hasan - Frontiers in medicine, 2020 - frontiersin.org
COVID-19, a disease induced by SARS-CoV-2 (Severe Acute Respiratory Syndrome
Coronavirus-2), has been the cause of a worldwide pandemic. Though extensive research …

Flavonoids: promising natural compounds against viral infections

H Zakaryan, E Arabyan, A Oo, K Zandi - Archives of virology, 2017 - Springer
Flavonoids are widely distributed as secondary metabolites produced by plants and play
important roles in plant physiology, having a variety of potential biological benefits such as …

Flavonoids as Antiviral Agents for Enterovirus A71 (EV-A71)

S Lalani, CL Poh - Viruses, 2020 - mdpi.com
Flavonoids are natural biomolecules that are known to be effective antivirals. These
biomolecules can act at different stages of viral infection, particularly at the molecular level to …

Promising antiviral activities of natural flavonoids against SARS-CoV-2 targets: systematic review

R Kaul, P Paul, S Kumar, D Büsselberg… - International journal of …, 2021 - mdpi.com
The ongoing COVID-19 pandemic, caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) became a globally leading public health concern over the past …

Safety and toxicity of silymarin, the major constituent of milk thistle extract: An updated review

V Soleimani, PS Delghandi, SA Moallem… - Phytotherapy …, 2019 - Wiley Online Library
Milk thistle (Silybum marianum) is a medicinal plant from the Asteraceae family. Silymarin is
the major constituent of milk thistle extract and is a mixture of some flavonolignans such as …

Antiviral strategies targeting host factors and mechanisms obliging+ ssRNA viral pathogens

S Mahajan, S Choudhary, P Kumar, S Tomar - Bioorganic & Medicinal …, 2021 - Elsevier
The ongoing COVID-19 pandemic, periodic recurrence of viral infections, and the
emergence of challenging variants has created an urgent need of alternative therapeutic …

Role of silymarin in cancer treatment: facts, hypotheses, and questions

T Koltai, L Fliegel - Journal of Evidence-Based Integrative …, 2022 - journals.sagepub.com
The flavonoid silymarin extracted from the seeds of Sylibum marianum is a mixture of 6
flavolignan isomers. The 3 more important isomers are silybin (or silibinin), silydianin, and …

[HTML][HTML] A scoping review of Chikungunya virus infection: epidemiology, clinical characteristics, viral co-circulation complications, and control

JVJ Silva Jr, LF Ludwig-Begall, EF de Oliveira-Filho… - Acta tropica, 2018 - Elsevier
Chikungunya fever is a mosquito-borne viral illness characterized by a sudden onset of
fever associated with joint pains. It was first described in the 1950s during a Chikungunya …

Mechanistic insights into the pharmacological significance of silymarin

K Wadhwa, R Pahwa, M Kumar, S Kumar, PC Sharma… - Molecules, 2022 - mdpi.com
Medicinal plants are considered the reservoir of diverse therapeutic agents and have been
traditionally employed worldwide to heal various ailments for several decades. Silymarin is a …

[HTML][HTML] Plant derived anticancer agents: A green approach towards skin cancers

S Ijaz, N Akhtar, MS Khan, A Hameed, M Irfan… - Biomedicine & …, 2018 - Elsevier
Plants have been used as medicinal agents since the origin of mankind. High cost and
severe side effects associated with conventional chemotherapy has limited their general …