Topological and geometric analysis of cell states in single-cell transcriptomic data

T Huynh, Z Cang - Briefings in Bioinformatics, 2024 - academic.oup.com
Single-cell RNA sequencing (scRNA-seq) enables dissecting cellular heterogeneity in
tissues, resulting in numerous biological discoveries. Various computational methods have …

Cycle registration in persistent homology with applications in topological bootstrap

Y Reani, O Bobrowski - IEEE Transactions on Pattern Analysis …, 2022 - ieeexplore.ieee.org
We propose a novel approach for comparing the persistent homology representations of two
spaces (or filtrations). Commonly used methods are based on numerical summaries such as …

Relational persistent homology for multispecies data with application to the tumor microenvironment

BJ Stolz, J Dhesi, JA Bull, HA Harrington… - Bulletin of mathematical …, 2024 - Springer
Topological data analysis (TDA) is an active field of mathematics for quantifying shape in
complex data. Standard methods in TDA such as persistent homology (PH) are typically …

Tracking the topology of neural manifolds across populations

IHR Yoon, G Henselman-Petrusek, Y Yu… - Proceedings of the …, 2024 - pnas.org
Neural manifolds summarize the intrinsic structure of the information encoded by a
population of neurons. Advances in experimental techniques have made simultaneous …

Fast topological signal identification and persistent cohomological cycle matching

I García-Redondo, A Monod, A Song - Journal of Applied and …, 2024 - Springer
Within the context of topological data analysis, the problems of identifying topological
significance and matching signals across datasets are important and useful inferential tasks …

Spherical coordinates from persistent cohomology

NC Schonsheck, SC Schonsheck - Journal of Applied and Computational …, 2024 - Springer
We describe a method to obtain spherical parameterizations of arbitrary data through the
use of persistent cohomology and variational optimization. We begin by computing the …

Topological Optimal Transport for Geometric Cycle Matching

SY Zhang, MPH Stumpf, T Needham… - arXiv preprint arXiv …, 2024 - arxiv.org
Topological data analysis is a powerful tool for describing topological signatures in real
world data. An important challenge in topological data analysis is matching significant …

Dowker duality, profunctors, and spectral sequences

IHR Yoon - arXiv preprint arXiv:2408.13136, 2024 - arxiv.org
The intent of this paper is to explore Dowker duality from a combinatorial, topological, and
categorical perspective. The paper presents three short, new proofs of Dowker duality using …

Distributed Persistent Homology for 2D Alpha Complexes

F Jensen, Á Torras-Casas - arXiv preprint arXiv:2403.00445, 2024 - arxiv.org
We introduce a new algorithm to parallelise the computation of persistent homology of 2D
alpha complexes. Our algorithm distributes the input point cloud among the cores which …

Additive Partial Matchings Induced by Persistence Morphisms

R Gonzalez-Diaz, M Soriano-Trigueros… - arXiv preprint arXiv …, 2020 - arxiv.org
Given a morphism of persistence modules (aka persistence morphism) $ f: V\rightarrow U $,
we introduce a novel operator that determines a partial matching between the barcodes of …