Osteoporosis in men is a common but often overlooked disorder by clinicians. The criterion
for osteoporosis diagnosis in men is similar to that in women—namely, a bone mineral …

Estrogens have historically been associated with female reproduction, but work over the last
two decades established that estrogens and their main nuclear receptors (ESR1 and ESR2) …

Changes in aging bone that lead to osteoporosis are mediated at multiple levels, including
hormonal alterations, skeletal unloading, and accumulation of senescent cells. This …

Estrogen is the key regulator of bone metabolism in both men and women. Menopause and
the accompanying loss of ovarian estrogens are associated with declines in bone mineral …

Testosterone is the most important hormone in male health. Aging is characterized by
testosterone deficiency due to decreasing testosterone levels associated with low testicular …

PURPOSE The aim of this work is to provide evidence-based guidance on the management
of osteoporosis in survivors of adult cancer. METHODS ASCO convened a multidisciplinary …

Improving physical function and mobility in a continuously expanding elderly population
emerges as a high priority of medicine today. Muscle mass, strength/power, and maximal …

Aging is associated with a loss of sex hormone in both men (andropause) and women
(menopause). In men, reductions in testosterone can trigger declines in muscle mass, bone …

Sex steroids are chief regulators of gender differences in the skeleton, and male gender is
one of the strongest protective factors against osteoporotic fractures. This advantage in bone …

Objective: The aim was to formulate practice guidelines for management of osteoporosis in
men. Evidence: We used the Grading of Recommendations, Assessment, Development, and …