Preeclampsia: novel mechanisms and potential therapeutic approaches
Z Armaly, JE Jadaon, A Jabbour, ZA Abassi - Frontiers in physiology, 2018 - frontiersin.org
Preeclampsia is a serious complication of pregnancy where it affects 5–8% of all
pregnancies. It increases the morbidity and mortality of both the fetus and pregnant woman …
pregnancies. It increases the morbidity and mortality of both the fetus and pregnant woman …
Research review on the pharmacological effects of astragaloside IV
L Li, X Hou, R Xu, C Liu, M Tu - Fundamental & clinical …, 2017 - Wiley Online Library
Astragalus membranaceus Bunge has been used to treat numerous diseases for thousands
of years. As the main active substance of Astragalus membranaceus Bunge, astragaloside …
of years. As the main active substance of Astragalus membranaceus Bunge, astragaloside …
Regulation of blood-retinal barrier cell-junctions in diabetic retinopathy
Loss of the blood-retinal barrier (BRB) integrity and subsequent damage to the
neurovascular unit in the retina are the underlying reasons for diabetic retinopathy (DR) …
neurovascular unit in the retina are the underlying reasons for diabetic retinopathy (DR) …
A multifaceted coating on titanium dictates osteoimmunomodulation and osteo/angio-genesis towards ameliorative osseointegration
L Bai, Z Du, J Du, W Yao, J Zhang, Z Weng, S Liu… - Biomaterials, 2018 - Elsevier
A multifaceted coating for hard tissue implants, with favorable osteogenesis, angiogenesis,
and osteoimmunomodulation abilities, would be of great value since it could improve …
and osteoimmunomodulation abilities, would be of great value since it could improve …
Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C–dependent buffering mechanism
A Machnik, W Neuhofer, J Jantsch, A Dahlmann… - Nature medicine, 2009 - nature.com
In salt-sensitive hypertension, the accumulation of Na+ in tissue has been presumed to be
accompanied by a commensurate retention of water to maintain the isotonicity of body fluids …
accompanied by a commensurate retention of water to maintain the isotonicity of body fluids …
Cardiovascular toxicity of angiogenesis inhibitors in treatment of malignancy: a systematic review and meta-analysis
Background The cardiovascular risk of angiogenesis inhibitors is not well-quantified. We
hypothesized that, compared to direct vascular endothelial growth factor (VEGF) inhibitors …
hypothesized that, compared to direct vascular endothelial growth factor (VEGF) inhibitors …
Vitamin D improves endothelial function in patients with Type 2 diabetes mellitus and low vitamin D levels
Aims To test whether a single large dose of vitamin D2 can improve endothelial function in
patients with Type 2 diabetes mellitus and low serum 25‐hydroxyvitamin D levels. Methods …
patients with Type 2 diabetes mellitus and low serum 25‐hydroxyvitamin D levels. Methods …
S-Nitrosylation in Cardiovascular Signaling
Well over 2 decades have passed since the endothelium-derived relaxation factor was
reported to be the gaseous molecule nitric oxide (NO). Although soluble guanylyl cyclase …
reported to be the gaseous molecule nitric oxide (NO). Although soluble guanylyl cyclase …
Dysregulation of hydrogen sulfide producing enzyme cystathionine γ-lyase contributes to maternal hypertension and placental abnormalities in preeclampsia
Background—The exact etiology of preeclampsia is unknown, but there is growing evidence
of an imbalance in angiogenic growth factors and abnormal placentation. Hydrogen sulfide …
of an imbalance in angiogenic growth factors and abnormal placentation. Hydrogen sulfide …
Negative regulation of soluble Flt-1 and soluble endoglin release by heme oxygenase-1
Background—Preeclampsia is characterized clinically by hypertension and proteinuria.
Soluble Flt-1 (sFlt-1; also known as soluble vascular endothelial growth factor receptor-1 …
Soluble Flt-1 (sFlt-1; also known as soluble vascular endothelial growth factor receptor-1 …