Bergapten: A review of its pharmacology, pharmacokinetics, and toxicity

Y Liang, L Xie, K Liu, Y Cao, X Dai… - Phytotherapy …, 2021 - Wiley Online Library
Bergapten is a natural furocoumarin, also known as 5‐methoxypsoralen, and its medicinal
value has been paid more and more attention. By sorting out the pharmacological literature …

Botanical sources, chemistry, analysis, and biological activity of furanocoumarins of pharmaceutical interest

R Bruni, D Barreca, M Protti, V Brighenti, L Righetti… - Molecules, 2019 - mdpi.com
The aim of this work is to provide a critical review of plant furanocoumarins from different
points of view, including their chemistry and biosynthetic pathways to their extraction …

[HTML][HTML] Chemistry and health effects of furanocoumarins in grapefruit

WL Hung, JH Suh, Y Wang - Journal of food and drug analysis, 2017 - Elsevier
Furanocoumarins are a specific group of secondary metabolites that commonly present in
higher plants, such as citrus plants. The major furanocoumarins found in grapefruits (Citrus …

Furocoumarins: A review of biochemical activities, dietary sources and intake, and potential health risks

MM Melough, E Cho, OK Chun - Food and chemical toxicology, 2018 - Elsevier
Furocoumarins are a class of chemical compounds with phototoxic properties found
naturally in many plant species, including some commonly consumed by humans (Dolan et …

Natural product coumarins: biological and pharmacological perspectives

MI Hussain, QA Syed, MNK Khattak, B Hafez… - Biologia, 2019 - Springer
Plants produce and release a vast variety of secondary metabolites with diversified
functions, and possess ecological, toxicological and biological effects that mimic the …

Taming food–drug interaction risk: Potential inhibitory effects of citrus juices on cytochrome liver enzymes can safeguard the liver from overdose paracetamol-induced …

AS Shalaby, HH Eid, RA El-Shiekh, OG Mohamed… - ACS …, 2023 - ACS Publications
Paracetamol overdose is the leading cause of drug-induced hepatotoxicity worldwide.
Because of N-acetyl cysteine's limited therapeutic efficacy and safety, searching for …

Overview of recent liquid chromatography mass spectrometry-based methods for natural toxins detection in food products

A De Girolamo, V Lippolis, M Pascale - Toxins, 2022 - mdpi.com
Natural toxins include a wide range of toxic metabolites also occurring in food and products,
thus representing a risk for consumer health. In the last few decades, several robust and …

Plant-derived natural coumarins with anticancer potentials: Future and challenges

A Gangopadhyay - Journal of Herbal Medicine, 2023 - Elsevier
Introduction This review provides an extensive summary of the anticancer property of new
natural coumarins. These coumarins comprise simple coumarin, furanocoumarin …

Affinity ultrafiltration and UPLC-HR-Orbitrap-MS based screening of neuraminidase inhibitors from Angelica pubescens

Z Tian, L Sun, B Chi, Z Du, X Zhang, Y Liu… - … of Chromatography B, 2022 - Elsevier
Traditional Chinese medicine is a rich source of natural products and has a long history of
use because of its remarkable clinical efficacy. In the present study, the chemical constitutes …

Identification and quantitation of furocoumarins in popularly consumed foods in the US using QuEChERS extraction coupled with UPLC-MS/MS analysis

MM Melough, SG Lee, E Cho, K Kim… - Journal of agricultural …, 2017 - ACS Publications
Furocoumarins are a class of photoactive compounds found in several plant species and
may be responsible for the observed association between consumption of citrus products …