When animals walk overground, mechanical stimuli activate various receptors located in
muscles, joints and skin. Afferents from these mechanoreceptors project to neuronal …

Pain is often perceived an unpleasant experience that includes sensory and
emotional/motivational responses. Accordingly, pain serves as a powerful teaching signal …

Thalamoreticular circuitry plays a key role in arousal, attention, cognition, and sleep
spindles, and is linked to several brain disorders. A detailed computational model of mouse …

The somatosensory system decodes a range of tactile stimuli to generate a coherent sense
of touch. Discriminative touch of the body depends on signals conveyed from peripheral …

Active sensing involves the fusion of internally generated motor events with external
sensation. For rodents, active somatosensation includes scanning the immediate …

Vibrations are ubiquitous in nature, shaping behavior across the animal kingdom. For
mammals, mechanical vibrations acting on the body are detected by mechanoreceptors of …

Forepaw somatosensory stimulation induces neural activities in relay thalamic nuclei, the
primary somatosensory cortex of forelimb (S1FL), and the secondary somatosensory cortex …

State-of-the-art upper extremity prostheses include anthropomorphic hands with dexterity
that approximates that of a human. To be fully useful, these devices will require an advanced …

Previous studies indicate that the dorsolateral striatum (DLS) integrates sensorimotor
information from cortical and thalamic regions to learn and execute motor habits. However …

Thalamocortical pathways from the rodent ventral posterior (VP) thalamic complex to the
somatosensory cerebral cortex areas are a key model in modern neuroscience. However …