The prefrontal cortex plays an important role in shaping cognition and behavior. Many
studies have shown that medial prefrontal cortex (mPFC) plays a key role in seeking …

Abstract Background and Aims Addiction is associated with severe economic and social
consequences and personal tragedies, the scientific exploration of which draws upon …

Major depressive disorder (MDD) has shown to negatively impact physical recovery in a
variety of medical events (eg, stroke and spinal cord injuries). Yet depression assessments …

Opioid-based drugs are frequently used for pain management in both males and females
despite the known risk of prefrontal cortex dysfunction and cognitive impairments. Although …

In addiction, an individual's ability to inhibit drug seeking and drug taking is thought to reflect
a pathological strengthening of drug-seeking behaviors or impairments in the capacity to …

Objective: A growing number of studies indicate increased impulsivity in patients with opioid
dependence (OD). However, few studies exclude concomitant drug use and consider …

BACKGROUND: Preclinical and clinical evidence show that the GABA B agonist, baclofen is
a promising treatment for addictive disorders; however, until recently its mechanism of action …

Background: Depressive symptoms are common in patients with Alzheimer's disease (AD)
and increase the caregiver burden, although the etiology and pathologic mechanism of …

Neuroimaging of opiate‐dependent individuals indicates both altered brain structure and
function. Magnetic resonance‐based arterial spin labeling has been used to measure …

目的探讨参加美沙酮维持治疗(MMT) 男性海洛因依赖患者的风险决策认知能力. 方法将45
例参加MMT 的男性患者及与其人口学资料相匹配的32 例健康对照组(HC) 作为研究对象 …