IL-6 is a pleiotropic cytokine with broad-ranging effects within the integrated immune
response. One of the roles of IL-6 is to support immunocompetence, defined as the ability of …

C-reactive protein (CRP) is an evolutionarily conserved protein. From arthropods to humans,
CRP has been found in every organism where the presence of CRP has been sought …

Pneumonia is a type of acute lower respiratory infection that is common and severe. The
outcome of lower respiratory infection is determined by the degrees to which immunity is …

C‐reactive protein (CRP) is an early‐stage acute phase protein and highly upregulated in
response to inflammatory reactions. We recently identified a novel mechanism that leads to …

Soluble pattern recognition molecules (PRMs) are a heterogenous group of proteins that
recognize pathogen-and danger-associated molecular patterns (PAMPs and DAMPs …

The phylogenetically ancient, pentraxin family of plasma proteins, comprises C-reactive
protein (CRP) and serum amyloid P component (SAP) in humans and the homologous …

One host defense function of C-reactive protein (CRP) is to protect against Streptococcus
pneumoniae infection as shown by experiments employing murine models of pneumococcal …

Obesity is characterized by low-grade chronic inflammation. As an acute-phase reactant to
inflammation and infection, C-reactive protein (CRP) has been found to be the strongest …

Amyotrophic lateral sclerosis (ALS) is a heterogeneous, progressive, and universally fatal
neurodegenerative disease. A subset of ALS patients has measurable plasma levels of …

Hepatic innate immune function plays an important role in the pathogenesis of many
diseases. Importantly, a growing body of literature has firmly established the spatial …