Pyrrole derivatives comprise a class of biologically active heterocyclic compounds which
can serve as promising scaffolds for antimicrobial, antiviral, antimalarial, antitubercular, anti …

Pyrrolo [2, 1-a] isoquinolines occur frequently in a large number of bioactive natural products
and pharmaceutically important molecules. The synthesis of pyrrolo [2, 1-a] isoquinoline …

Nitrogen heterocycles are essential parts of the chemical machinery of life and often reveal
intriguing structures. They are not only widespread in terrestrial habitats but can also …

In 1985 the first lamellarins were isolated from a small oceanic sea snail. Today, more than
50 lamellarins have been inventoried and numerous derivatives synthesized and tested as …

Lamellarins are marine alkaloids containing fused 14-phenyl-6H-[1] benzopyrano [4′, 3′:
4, 5] pyrrolo [2, 1-a] isoquinoline or non-fused 3, 4-diarylpyrrole-2-carboxylate ring systems …

We have developed a copper-catalyzed synthesis of pyrrolo [2, 1-a] isoquinolines with
terminal alkynes, aldehydes, and tetrahydroisoquinolines. A variety of pyrrolo [2, 1-a] …

In this investigation, we synthesized novel Cu-porphyrazines annulated with diazepines
moiteis, the diazepines rings were obtained via 1, 4-cycloaddition reactions of chalcone …

Bridgehead nitrogen (or ring-junction nitrogen) heterocycles are one of the most privileged
scaffolds in synthetic chemistry and medicinal chemistry. For decades, transition metal …

This report summarizes the latest published data on the antiproliferative action and cytotoxic
activity of Mannich bases, a structurally heterogeneous category of chemical entities that …

We have developed a straightforward FeCl3 promoted synthesis of dihydropyrrolo [2, 1‐a]
isoquinolines through formal (3+ 2) cycloaddition/oxidative aromatization cascade of …