Gene network analysis of oxaliplatin-resistant colorectal cancer to target a crucial gene using chitosan/hyaluronic acid/protamine polyplexes containing CRISPR-Cas9
Colorectal cancer (CRC) treatment is dramatically hampered by resistance to oxaliplatin
alone or in the combination of irinotecan or 5-fluorouracil and leucovorin. This study aims to …
alone or in the combination of irinotecan or 5-fluorouracil and leucovorin. This study aims to …
The Ability of Polymorphisms in DNA Repair Enzymes to Predict Clinical Outcome in Colorectal Cancer Patients
K Gajjar, T Kobawala, H Vora… - Middle East Journal of …, 2020 - mejc.sums.ac.ir
Background: Genomic polymorphisms of DNA repair enzymes/excision repair cross
complementation group 1 (ERCC1), excision repair cross complementation group 2 …
complementation group 1 (ERCC1), excision repair cross complementation group 2 …
Prognostic and Predictive Role of Excision Repair Cross-complementation Group 1 and Thymidylate Synthase in Colorectal Carcinoma Patients Received FOLFOX …
Results: The data analysis showed that high ERCC-1 and TS expression was significantly
associated with early treatment failure (P= 0.020 and 0.000). In contrast, TS …
associated with early treatment failure (P= 0.020 and 0.000). In contrast, TS …
[PDF][PDF] Prognostic and Predictive Value of ERCC1, ERCC2 and XRCC1 Protein Expression in Colorectal Cancer Patients
K Gajjar, T Mandalia, H Vora, N Ghosh - researchgate.net
The DNA repair enzymes ERCC1, ERCC2 and XRCC1 play a major role in the repair of
platinum-DNA adduct formation. These proteins may affect survival of colorectal cancer …
platinum-DNA adduct formation. These proteins may affect survival of colorectal cancer …
ERCC1 and MGMT Methylation as a Predictive Marker of Relapse and FOLFOX Response in Colorectal Cancer Patients from South Tunisia
D Jamai, R Gargouri, B Selmi, A Khabir - Genes, 2023 - mdpi.com
Genetic and epigenetic modifications present a major cause of relapse and treatment failure
in colorectal cancer. This study aims to appreciate the prognostic and predictive value of …
in colorectal cancer. This study aims to appreciate the prognostic and predictive value of …