Advances in research on type 2 diabetes mellitus targets and therapeutic agents

J Su, Y Luo, S Hu, L Tang, S Ouyang - International Journal of Molecular …, 2023 - mdpi.com
Diabetes mellitus is a chronic multifaceted disease with multiple potential complications, the
treatment of which can only delay and prolong the terminal stage of the disease, ie, type 2 …

Gut microbiota dysbiosis in polycystic ovary syndrome: Mechanisms of progression and clinical applications

Y Sun, S Gao, C Ye, W Zhao - Frontiers in cellular and infection …, 2023 - frontiersin.org
Polycystic ovary syndrome (PCOS) is the most common endocrine diseases in women of
childbearing age that leads to menstrual disorders and infertility. The pathogenesis of PCOS …

[HTML][HTML] Butyrate: A potential mediator of obesity and microbiome via different mechanisms of actions

MS Güler, S Arslan, D Ağagündüz, I Cerqua… - Food Research …, 2024 - Elsevier
Butyrate, a short-chain fatty acid, is a crucial product of gut microbial fermentation with
significant implications for various metabolic and physiological processes. Dietary sources …

Omics biomarkers and an approach for their practical implementation to delineate health status for personalized nutrition strategies

J Keijer, X Escoté, S Galmés… - Critical reviews in …, 2024 - Taylor & Francis
Personalized nutrition (PN) has gained much attention as a tool for empowerment of
consumers to promote changes in dietary behavior, optimizing health status and preventing …

[HTML][HTML] The role of gut microbiome-derived short chain fatty acid butyrate in hepatobiliary diseases

K Pant, SK Venugopal, MJL Pisarello… - The American Journal of …, 2023 - Elsevier
The multiple beneficial effects of the short-chain fatty acid (SCFA) butyrate on human health,
produced from fermentable carbohydrates by gut microbiota in the colon, are well known. At …

Gut microbiota and derived short-chain fatty acids are linked to evolution of heart failure patients

J Modrego, A Ortega-Hernández… - International journal of …, 2023 - mdpi.com
There is a lack of direct evidence regarding gut microbiota dysbiosis and changes in short-
chain fatty acids (SCFAs) in heart failure (HF) patients. We sought to assess any association …

Microbial metabolites as modulators of host physiology

SA Joyce, DJ Clarke - Advances in Microbial Physiology, 2024 - Elsevier
The gut microbiota is increasingly recognised as a key player in influencing human health
and changes in the gut microbiota have been strongly linked with many non-communicable …

[HTML][HTML] Cellular and molecular pathophysiology of gestational diabetes

J Torres-Torres, IE Monroy-Muñoz… - International Journal of …, 2024 - mdpi.com
Gestational diabetes (GD) is a metabolic disorder characterized by glucose intolerance
during pregnancy, significantly impacting maternal and fetal health. Its global prevalence is …

[HTML][HTML] Targeting Gut microbiota as a therapeutic target in T2DM: a review of Multi-target interactions of probiotics, prebiotics, postbiotics, and synbiotics with the …

K Chen, H Wang, X Yang, C Tang, G Hu… - Pharmacological Research, 2024 - Elsevier
The global epidemic of type 2 diabetes mellitus (T2DM) imposes a substantial burden on
public health and healthcare expenditures, thereby driving the pursuit of cost-effective …

Carbohydrate quality, fecal microbiota and cardiometabolic health in older adults: a cohort study

A Atzeni, SK Nishi, N Babio, C Belzer, P Konstanti… - Gut …, 2023 - Taylor & Francis
The impact of carbohydrate quality, measured by the carbohydrate quality index (CQI), on
gut microbiota and health has been scarcely investigated. The aim of this study was to cross …