Latest developments in molecular tracers for fluorescence image-guided cancer surgery

S Hernot, L van Manen, P Debie, JSD Mieog… - The lancet …, 2019 - thelancet.com
Real-time intraoperative guidance is essential during oncological surgery for complete and
safe tumour resection. Fluorescence imaging in the near-infrared spectrum has shown …

Advanced nanotechnology leading the way to multimodal imaging‐guided precision surgical therapy

C Wang, W Fan, Z Zhang, Y Wen, L Xiong… - Advanced …, 2019 - Wiley Online Library
Surgical resection is the primary and most effective treatment for most patients with solid
tumors. However, patients suffer from postoperative recurrence and metastasis. In the past …

[HTML][HTML] A DROP-IN gamma probe for robot-assisted radioguided surgery of lymph nodes during radical prostatectomy

P Dell'Oglio, P Meershoek, T Maurer, EMK Wit… - European Urology, 2021 - Elsevier
Abstract Background The DROP-IN gamma probe was introduced to overcome the restricted
manoeuvrability of traditional laparoscopic gamma probes. Through enhanced …

Hybrid indocyanine green–99mTc-nanocolloid for single-photon emission computed tomography and combined radio-and fluorescence-guided sentinel node biopsy …

P Dell'Oglio, HM de Vries, E Mazzone, GH KleinJan… - European Urology, 2020 - Elsevier
Background Sentinel node (SN) biopsy in penile cancer (PeCa) is typically performed using
99m Tc-nanocolloid and blue dye. Recent reports suggested that the hybrid (radioactive and …

The EANM practical guidelines for sentinel lymph node localisation in oral cavity squamous cell carcinoma

F Giammarile, C Schilling, G Gnanasegaran… - European journal of …, 2019 - Springer
Purpose Sentinel lymph node biopsy is an essential staging tool in patients with clinically
localized oral cavity squamous cell carcinoma. The harvesting of a sentinel lymph node …

How molecular imaging will enable robotic precision surgery: the role of artificial intelligence, augmented reality, and navigation

T Wendler, FWB van Leeuwen, N Navab… - European Journal of …, 2021 - Springer
Molecular imaging is one of the pillars of precision surgery. Its applications range from early
diagnostics to therapy planning, execution, and the accurate assessment of outcomes. In …

Recent advances in nuclear and hybrid detection modalities for image-guided surgery

MN Van Oosterom, DDD Rietbergen… - Expert review of …, 2019 - Taylor & Francis
Introduction: Radioguided surgery is an ever-evolving part of nuclear medicine. In fact, this
nuclear medicine sub-discipline actively bridges non-invasive molecular imaging with …

Artificial Intelligence‐Supported Video Analysis as a Means to Assess the Impact of DROP‐IN Image Guidance on Robotic Surgeons: Radioguided Sentinel Lymph …

S Azargoshasb, HA de Barros… - Advanced Intelligent …, 2023 - Wiley Online Library
The introduction of the tethered DROP‐IN gamma probe has enabled targeted robot‐
assisted radioguided prostate cancer (PCa) resection of pelvic sentinel lymph nodes (SLNs) …

[HTML][HTML] PSMA-targeting agents for radio-and fluorescence-guided prostate cancer surgery

YHW Derks, DWPM Löwik, JPM Sedelaar… - Theranostics, 2019 - ncbi.nlm.nih.gov
Despite recent improvements in imaging and therapy, prostate cancer (PCa) still causes
substantial morbidity and mortality. In surgical treatment, incomplete resection of PCa and …

Precision surgery guided by intraoperative molecular imaging

F Azari, K Zhang, GT Kennedy, A Chang… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Intraoperative molecular imaging (IMI) has recently emerged as an important tool in the
armamentarium of surgical oncologists. IMI allows real-time assessment of oncologic …