Inflammation and lymphatic function

S Schwager, M Detmar - Frontiers in immunology, 2019 - frontiersin.org
The lymphatic vasculature plays a crucial role in regulating the inflammatory response by
influencing drainage of extravasated fluid, inflammatory mediators, and leukocytes …

[HTML][HTML] The hepatic lymphatic vascular system: structure, function, markers, and lymphangiogenesis

M Tanaka, Y Iwakiri - Cellular and molecular gastroenterology and …, 2016 - Elsevier
The lymphatic vascular system has been minimally explored in the liver despite its essential
functions including maintenance of tissue fluid homeostasis. The discovery of specific …

The interplay between lymphatic vessels and chemokines

RH Farnsworth, T Karnezis, SJ Maciburko… - Frontiers in …, 2019 - frontiersin.org
Chemokines are a family of small protein cytokines that act as chemoattractants to migrating
cells, in particular those of the immune system. They are categorized functionally as either …

Lymphatic vessels: new targets for the treatment of inflammatory diseases

LC Dieterich, CD Seidel, M Detmar - Angiogenesis, 2014 - Springer
The lymphatic system plays an important role in the physiological control of the tissue fluid
balance and in the initiation of immune responses. Recent studies have shown that …

Therapeutic Lymphangiogenesis is a promising strategy for secondary lymphedema

Y Shimizu, Y Che, T Murohara - International journal of molecular …, 2023 - mdpi.com
Secondary lymphedema is caused by lymphatic insufficiency (lymphatic drainage failure)
following lymph node dissection during the surgical treatment or radiation therapy of breast …

The inflammatory response of lymphatic endothelium

D Aebischer, M Iolyeva, C Halin - Angiogenesis, 2014 - Springer
Lymphatic vessels have traditionally been regarded as a rather inert drainage system, which
just passively transports fluids, leukocytes and antigen. However, it is becoming increasingly …

Adipose-derived stem cells promote proliferation, migration, and tube formation of lymphatic endothelial cells in vitro by secreting lymphangiogenic factors

K Takeda, Y Sowa, K Nishino, K Itoh… - Annals of plastic …, 2015 - journals.lww.com
Adipose-derived stem cells (ADSCs) are a promising new therapeutic modality for several
diseases and have been applied to various clinical fields because of their multidifferentiation …

Potential lymphangiogenesis therapies: Learning from current antiangiogenesis therapies—A review

M Yamakawa, SJ Doh, SM Santosa… - Medicinal research …, 2018 - Wiley Online Library
In recent years, lymphangiogenesis, the process of lymphatic vessel formation from existing
lymph vessels, has been demonstrated to have a significant role in diverse pathologies …

Adipose tissue and biological factors. Possible link between lymphatic system dysfunction and obesity

K Antoniak, R Hansdorfer-Korzon, M Mrugacz… - Metabolites, 2021 - mdpi.com
The World Health Organization (WHO) has recognised obesity as one of the top ten threats
to human health. Obesity is not only a state of abnormally increased adipose tissue in the …

Lymphangiogenesis and angiogenesis in abdominal aortic aneurysm

M Sano, T Sasaki, S Hirakawa, J Sakabe, M Ogawa… - PLoS …, 2014 - journals.plos.org
The pathogenesis of abdominal aortic aneurysm (AAA) is characterized to be inflammation-
associated degeneration of vascular wall. Neovascularization is regularly found in human …