Many pharmaceuticals such as pills, capsules, or tablets are prepared in a dried and
powdered form. In this field, spray drying plays a critical role to convert liquid pharmaceutical …

Introduction: Early dry powder inhalers (DPIs) were designed for low drug doses in asthma
and COPD therapy. Nearly all concepts contained carrier-based formulations and lacked …

Introduction: Respiratory drug delivery is a surprisingly complex process with a number of
physical and biological challenges. Computational fluid dynamics (CFD) is a scientific …

This chapter introduces the nano spray drying technique and discusses its unique features
and process engineering aspects, as well as its application in the nanoencapsulation of food …

For about 15 years the performance of dry powder inhalers (DPIs) has been numerically
analysed through CFD (computational fluid dynamics) approaches with the objective of …

Background: The objective of this study was to compare aerosol deposition predictions of a
new whole-airway CFD model with available in vivo data for a dry powder inhaler (DPI) …

Introduction: The number of pulmonary diseases that are effectively treated by aerosolized
medicine continues to grow. Areas covered: These diseases include chronic obstructive …

Spray drying plays a crucial role in the processing of pharmaceutical products such as pills,
capsules, and tablets as it is used to convert drug-containing liquids into dried powdered …

Capsule-based dry powder inhalers (cDPIs) are widely utilized in the delivery of
pharmaceutical powders to the lungs. In these systems, the fundamental nature of the …

Significant progress has been made over the last half-century in delivering therapeutics by
the pulmonary route. Inhaled therapeutics are administered to humans using metered-dose …