Background The use of neonicotinoids (NEOs) has been rising globally due to their broad-
spectrum insecticidal activity and unique mode of neurotoxic action. However, the residues …

Unraveling the complexities of brain function, which is crucial for advancing human health,
remains a grand challenge. This endeavor demands precise monitoring of small molecules …

Biosensors have been explored for their application in analytical assays with an increasing
reliance on nanomaterials and biomolecule recognition units. Recently, magnetic …

Background Aptamers are screened via the systematic evolution of ligands by exponential
enrichment (SELEX) and are widely used in molecular diagnostics and targeted therapies …

The existing aptamers for cadmium (Cd2+), the common toxic heavy metal contaminant in
food, cannot meet the requirements for detecting Cd2+ in rapid detection methods. In …

Bile acids are one of the most important steroid compounds in liver, providing vital
bioinformation and clinical evidence for disease surveillance. Abnormal concentrations of …

The emergence and rapid spread of Mpox (formerly monkeypox) have caused significant
societal challenges. Adequate and appropriate diagnostics procedures are an urgent …

Aptamers, as short single-stranded nucleic acids, can bind to targets in a similar way to
antibodies. Relying on the advantages of low cost, high stability, and flexibility, they are …

Infectious diseases represent a significant global health challenge, with bacteria, fungi,
viruses, and parasitic protozoa being significant causative agents. The shared symptoms …

Circular aptamers are promising candidates for analytical and therapeutic applications due
to their enhanced biological and structural stability. However, the process of circular aptamer …