Checkpoint inhibitor-induced colitis: From pathogenesis to management

M Terrin, G Migliorisi, A Dal Buono… - International Journal of …, 2023 - mdpi.com
The advent of immunotherapy, specifically of immune checkpoint inhibitors (ICIs), for the
treatment of solid tumors has deeply transformed therapeutic algorithms in medical …

Checkpoint inhibitor-induced colitis: an update

G Losurdo, D Angelillo, N Favia, MC Sergi, A Di Leo… - Biomedicines, 2023 - mdpi.com
Immunotherapy with immune checkpoint inhibitors (ICIs) nowadays has indications for
several solid tumors. The current targets for ICIs are CTLA-4, PD-1, and PD-L1 receptors …

Systematic review with meta-analysis: The impact of cancer treatments on the disease activity of inflammatory bowel diseases

S Grimsdottir, M Attauabi, E Kristine Dahl… - Journal of Crohn's …, 2023 - academic.oup.com
Abstract Background and Aims The association between cancer treatments and
exacerbation of inflammatory bowel diseases [IBD] is unclear. We aimed to evaluate the …

Potential Immunotherapy Targets for Liver-Directed Therapies, and the Current Scope of Immunotherapeutics for Liver-Related Malignancies

J Charles, A Vrionis, A Mansur, T Mathias, J Shaikh… - Cancers, 2023 - mdpi.com
Simple Summary Liver cancer continues to exhibit increasing incidence and mortality
worldwide. Subsequently, there has been a concomitant effort to development novel …

Management of Inflammatory Bowel Disease in Patients with Current or Past Malignancy

F Poullenot, D Laharie - Cancers, 2023 - mdpi.com
Simple Summary Physicians face therapeutic choices in an increasing number of IBD
patients with current or past malignancy. Even if uncontrolled IBD may lead to severe …

Contemporary management of gastrointestinal, pancreatic and hepatic toxicities of immune checkpoint inhibitors

MJ Townsend, IJ Benque, M Li… - Alimentary …, 2024 - Wiley Online Library
Summary Background Immune checkpoint inhibitors (ICIs) are effective oncologic agents
which frequently cause immune‐related adverse events (irAEs) which can impact multiple …

[HTML][HTML] High iNOS and IL-1β immunoreactivity are features of colitis-associated colorectal cancer tumors, but fail to predict 5-year survival

K Björner, WN Chen, VR Gannavarapu… - Upsala Journal of …, 2023 - ncbi.nlm.nih.gov
Background Inflammatory bowel disease (IBD; mainly ulcerative colitis and Crohn's disease)
is associated with the development of colorectal cancer (CRC) referred to as colitis …

Immunosuppressive therapy management in cancer patients with autoimmune diseases treated with immune checkpoint inhibitors: A case series and systematic …

SCM Wuyts, CAH Cappelle… - Journal of Oncology …, 2024 - journals.sagepub.com
Introduction Prescribing immune checkpoint inhibitors (ICIs) to cancer patients with an
autoimmune disease (AID) is presumed safe when cautious adverse event management is …

Immune check-point inhibitors related enterocolitis

L Marthey, R Abdallah, C Bellanger, C Bresteau… - Hépato-Gastro & …, 2023 - jle.com
▼ Résumé L'immunothérapie des cancers est en plein développement. Les inhibiteurs de
point de contrôle immunitaire (ICI), c'est-à-dire les anticorps anti-CTLA4 et anti-PD1, sont à …

Les entérocolites aux inhibiteurs de point de contrôle immunitaire.

L Marthey, R Abdallah, C Bellanger… - Hepato-Gastro & …, 2023 - search.ebscohost.com
English Immunotherapy in cancer is coming of age. Immune checkpoint inhibitors (ICI),
namely anti-CTLA4 and anti-PD1 antibodies, can lead to immune-related adverse events …