Salivary Diagnostics—Point-of-Care diagnostics of MMP-8 in dentistry and medicine

N Rathnayake, DR Gieselmann, AM Heikkinen… - Diagnostics, 2017 - mdpi.com
Human saliva is an easily accessible biological fluid and contains a variety of disease-
related biomarkers, which makes it a potential diagnostic medium. The clinical use of …

The potential impact of salivary peptides in periodontitis

C Hirtz, R O'Flynn, PM Voisin… - Critical reviews in …, 2021 - Taylor & Francis
Periodontitis is a complex immune-inflammatory condition characterized by the disruption of
the periodontal ligament and subsequent formation of periodontal pockets, and by alveolar …

Intrapocket application of tea tree oil gel in the treatment of stage 2 periodontitis

MR Taalab, SA Mahmoud, RME Moslemany… - BMC Oral Health, 2021 - Springer
Background The gold standard in treatment of periodontitis is mechanical removing of dental
biofilm but using local delivery drugs as adjunctive to SRP is widely used to modulate …

Determination of the accuracy of salivary biomarkers for periodontal diagnosis

HA Mohammed, AA Abdulkareem, FM Zardawi, SS Gul - Diagnostics, 2022 - mdpi.com
Background: We aimed to investigate the accuracy of salivary matrix metalloproteinases
(MMP)-8 and-9, and tissue inhibitor of metalloproteinase (TIMP)-1 in diagnosing …

Ability of matrix metalloproteinase‐8 biosensor, IFMA, and ELISA immunoassays to differentiate between periodontal health, gingivitis, and periodontitis

KA Umeizudike, H Lähteenmäki… - Journal of …, 2022 - Wiley Online Library
Objective The aim of this study was to determine the diagnostic utility of an MMP‐8
biosensor assay in differentiating periodontal health from gingivitis and periodontitis and …

Active matrix metalloproteinase-8 point-of-care (PoC)/chairside mouthrinse test vs. bleeding on probing in diagnosing subclinical periodontitis in adolescents

IT Räisänen, T Sorsa, GJ van der Schoor… - Diagnostics, 2019 - mdpi.com
This cross-sectional study compares the effectiveness of an active MMP-8 (aMMP-8) point-of-
care (PoC)/chairside mouthrinse test to the conventional bleeding on probing (BOP)(cutoff …

Salivary metalloproteinase-8 and metalloproteinase-9 evaluation in patients undergoing fixed orthodontic treatment before and after periodontal therapy

IA Sioustis, MA Martu, L Aminov, M Pavel… - International Journal of …, 2021 - mdpi.com
(1) Background: Metalloproteinase-8 (MMP-8) and metalloproteinase-9 (MMP-9) are
members of a family of proteases of major importance during orthodontic tooth movement …

Pilot study on the genetic background of an active matrix metalloproteinase‐8 test in finnish adolescents

AM Heikkinen, T Raivisto, K Kettunen… - Journal of …, 2017 - Wiley Online Library
Background: In periodontitis, genetics and smoking play important roles in host immune
system response. The aim of this study is to determine whether the genetic background of …

Evaluation of metalloproteinase‐8 levels in crevicular fluid of patients with healthy implants or periodontitis

P Aleksandrowicz, P Żelechowska… - Mediators of …, 2017 - Wiley Online Library
Evaluation of periodontal and peri‐implant tissue condition is mainly based on clinical
examination and imaging diagnostics. Some data imply that Metalloproteinase‐8 (MMP‐8) …

A point‐of‐care test of active matrix metalloproteinase‐8 predicts triggering receptor expressed on myeloid cells‐1 (TREM‐1) levels in saliva

IT Räisänen, AM Heikkinen… - Journal of …, 2020 - Wiley Online Library
Background This cross‐sectional study aims to investigate if a point‐of‐care (PoC) test of
active matrix metalloproteinase‐8 (aMMP‐8) predicts levels of inflammation amplifier …