Recombinant Human Thymosin Beta‐4 Protects against Mouse Coronavirus Infection

R Yu, Y Mao, K Li, Y Zhai, Y Zhang, S Liu… - Mediators of …, 2021 - Wiley Online Library
Coronaviruses (CoVs) are enveloped and harbor an unusually large (30–32 kb) positive‐
strand linear RNA genome. Highly pathogenic coronaviruses cause severe acute respiratory …

The effect of desloratadine on ischemia reperfusion induced oxidative and inflammatory renal injury in rats

H Kocaturk, F Bedir, MS Altay, E Bakan, B Suleyman… - Renal failure, 2020 - Taylor & Francis
Purpose To examine the effect of desloratadine on kidney ischemia-reperfusion (I/R) injury
in albino Wistar male rats using biochemical and histopathological methods. Methods The …

[HTML][HTML] Association between Thymosin beta-4, acute kidney injury, and mortality in patients with sepsis: An observational cohort study

J Zhang, M Long, Z Sun, C Yang, X Jiang, L He… - International …, 2021 - Elsevier
Background Sepsis is a systemic inflammatory response syndrome, associated with high
risk of acute kidney injury (AKI) and in-hospital mortality. Thymosin beta-4 (Tβ4) is an actin …

Systemic gene therapy with thymosin β4 alleviates glomerular injury in mice

WJ Mason, DJ Jafree, G Pomeranz… - Scientific Reports, 2022 - nature.com
Plasma ultrafiltration in the kidney occurs across glomerular capillaries, which are
surrounded by epithelial cells called podocytes. Podocytes have a unique shape maintained …

Thymosin Β4 Alleviated Sepsis-Associated Acute Kidney Injury Via Inhibiting Mapk Signaling Pathway

X Ouyang, Z Long, X Xu, M Jiang, Y Pei, B Jin… - Available at SSRN … - papers.ssrn.com
Aims: Sepsis-associated acute kidney injury (SA-AKI) is prevalent in septic patients, leading
to a higher mortality or progression to chronic kidney disease (CKD). Thymosin β4 (Tβ4) …

[PDF][PDF] Systemic gene therapy with thymosin b4 alleviates glomerular injury in mice

WJ Mason, DJ Jafree, G Pomeranz, M Kolatsi-Joannou… - rvc-repository.worktribe.com
Results ADR is associated with the downregulation of TB4 in podocytes. ADR, a
chemotherapeutic drug, replicates some of the features of human focal segmental …

[PDF][PDF] Thymosin Beta 4 as an Early Biomarker in Sepsis Induced Acute Kidney Injury

J Zhang, M Long, Z Sun, C Yang, X Jiang, L He, L Su… - 2021 - scholar.archive.org
Background: The incidence of sepsis is high among patients in the intensive care units (ICU)
and acute kidney injury (AKI) is a common complication of sepsis that contributes to …