Hydrolysis, Ligand Exchange, and Redox Properties of Vanadium Compounds: Implications of Solution Transformation on Biological, Therapeutic, and Environmental …

R Dinda, E Garribba, D Sanna, DC Crans… - Chemical …, 2025 - ACS Publications
Vanadium is a transition metal with important industrial, technological, biological, and
biomedical applications widespread in the environment and in living beings. The different …

Vanadium and melanoma: A systematic review

C Amante, AL De Sousa-Coelho, M Aureliano - Metals, 2021 - mdpi.com
The application of metals in biological systems has been a rapidly growing branch of
science. Vanadium has been investigated and reported as an anticancer agent. Melanoma …

Substitution kinetics, albumin and transferrin affinities, and hypoxia all affect the biological activities of anticancer vanadium (V) complexes

A Levina, C Uslan, H Murakami, DC Crans… - Inorganic …, 2023 - ACS Publications
Limited stability of most transition-metal complexes in biological media has hampered their
medicinal applications but also created a potential for novel cancer treatments, such as …

Correlation of the anticancer and pro-oxidant behavior and the structure of flavonoid-oxidovanadium (IV) complexes

LG Naso, EG Ferrer, PAM Williams - Coordination Chemistry Reviews, 2023 - Elsevier
The phytochemical compounds flavonoids have potential medicinal benefits such as
antioxidant, anti-inflammatory, anticancer and antiviral action. These properties can be …

Vanadium (V) Pyridine‐Containing Schiff Base Catecholate Complexes are Lipophilic, Redox‐Active and Selectively Cytotoxic in Glioblastoma (T98G) Cells

K Kostenkova, A Levina, DA Walters… - … A European Journal, 2023 - Wiley Online Library
Two new series of complexes with pyridine‐containing Schiff bases,[VVO (SALIEP) L] and
[VVO (Cl‐SALIEP) L](SALIEP= N‐(salicylideneaminato)‐2‐(2‐aminoethylpyridine; Cl …

The viral knock: ameliorating cancer treatment with oncolytic Newcastle disease virus

U Pathak, RB Pal, N Malik - Life, 2023 - mdpi.com
The prospect of cancer treatment has drastically transformed over the last four decades. The
side effects caused by the traditional methods of cancer treatment like surgery …

Development of molecular mechanisms and their application on oncolytic Newcastle disease virus in cancer therapy

F Huang, C Dai, Y Zhang, Y Zhao, Y Wang… - Frontiers in Molecular …, 2022 - frontiersin.org
Cancer is caused by the destruction or mutation of cellular genetic materials induced by
environmental or genetic factors. It is defined by uncontrolled cell proliferation and …

Synergistic cytotoxicity of olive leaf extract-loaded lipid nanocarriers combined with Newcastle disease virus against cervical cancer cells

A Golalipour, A Mohammadi, S Hosseinzadeh… - Plos one, 2024 - journals.plos.org
Despite recent medical progress, cervical cancer remains a major global health concern for
women. Current standard treatments have limitations such as non-specific toxicity that …

Solution chemistry and anti-proliferative activity against glioblastoma cells of a vanadium (V) complex with two bioactive ligands

A Levina, G Scalese, D Gambino, DC Crans… - Frontiers in Chemical …, 2024 - frontiersin.org
Introduction: Glioblastoma is a brain cancer difficult to treat but recently mixed-ligand
vanadium (V) Schiff base/catecholato complexes have exhibited high in vitro anti …

Vanadyl sulfate-enhanced oncolytic virus immunotherapy mediates the antitumor immune response by upregulating the secretion of pro-inflammatory cytokines and …

N Alluqmani, A Jirovec, Z Taha, O Varette… - Frontiers in …, 2022 - frontiersin.org
Oncolytic viruses (OVs) are promising anticancer treatments that specifically replicate in and
kill cancer cells and have profound immunostimulatory effects. We previously reported the …