Strategies for capillary electrophoresis: method development and validation for pharmaceutical and biological applications—updated and completely revised edition

F Krebs, H Zagst, M Stein, R Ratih, R Minkner… - …, 2023 - Wiley Online Library
This review is in support of the development of selective, precise, fast, and validated
capillary electrophoresis (CE) methods. It follows up a similar article from 1998, Wätzig H …

Detection of biosignatures by capillary electrophoresis mass spectrometry in the presence of salts relevant to ocean worlds missions

MF Mora, MGM Kok, A Noell, PA Willis - Astrobiology, 2022 - liebertpub.com
Capillary electrophoresis (CE) is a promising liquid-based technique for in situ chemical
analysis on ocean worlds that allows the detection of a wide range of organic molecules …

A gravity‐independent single‐phase electrode reservoir for capillary electrophoresis applications

T Drevinskas, AC Noell, F Kehl, K Zamuruyev… - …, 2023 - Wiley Online Library
Capillary electrophoresis (CE) holds great promise as an in situ analytical technique for a
variety of applications. However, typical instrumentation operates with open reservoirs (eg …

Contactless Conductivity Detection for Capillary Electrophoresis—Developments From 2020 to 2024

PC Hauser, P Kubáň - Electrophoresis, 2024 - Wiley Online Library
The review covering the development of capillary electrophoresis with capacitively coupled
contactless conductivity detection from 2020 to 2024 is the latest in a series going back to …

[HTML][HTML] Europan molecular indicators of life investigation (EMILI) for a future Europa lander mission

WB Brinckerhoff, PA Willis, AJ Ricco… - Frontiers in Space …, 2022 - frontiersin.org
The Europan Molecular Indicators of Life Investigation (EMILI) is an instrument concept
being developed for the Europa Lander mission currently under study. EMILI will meet and …

From microorganisms to biosignatures: Subcritical water extraction as a sample preparation technique for future life detection missions

Z Cieslarova, AC Noell, PA Willis… - Geophysical Research …, 2022 - Wiley Online Library
Amino acids are important targets in the search for life beyond Earth. The types of amino
acids, their relative abundances, and enantiomeric excess all serve as biosignatures. To …

Onboard science instrument autonomy for the detection of microscopy biosignatures on the ocean worlds life surveyor

M Wronkiewicz, J Lee, L Mandrake… - The Planetary …, 2024 - iopscience.iop.org
The quest to find extraterrestrial life is a critical scientific endeavor with civilization-level
implications. Icy moons in our solar system are promising targets for exploration because …

Towards a radiation-tolerant contactless conductivity detector for use with capillary electrophoresis systems in spaceflight applications

MSF Santos, BC Metz, ET da Costa, CL do Lago… - Acta Astronautica, 2022 - Elsevier
The simplicity, versatility, and ease of miniaturization of capillary electrophoresis with
capacitively coupled contactless conductivity detection (CE-C 4 D) has led to its application …

Microfluidic chromatography for enhanced amino acid detection at Ocean Worlds

T Van Volkenburg, JS Benzing, KL Craft, K Ohiri… - Astrobiology, 2022 - liebertpub.com
Increasing interest in the detection of biogenic signatures, such as amino acids, on icy
moons and bodies within our solar system has led to the development of compact in situ …

Effect of pH on the Release of Amino Acids from Microorganisms via Subcritical Water Extraction

Z Cieslarova, MF Mora, AC Noell… - ACS Earth and Space …, 2024 - ACS Publications
Distributions of amino acids, based on either enantiomeric excess or relative abundances of
amino acid type, are key chemical measurements in the search for life on potential future …