Mechanisms of protein import into mitochondria

KN Truscott, K Brandner, N Pfanner - Current Biology, 2003 - cell.com
Apart from a handful of proteins encoded by the mitochondrial genome, most proteins
residing in this organelle are nuclear-encoded and synthesised in the cytosol. Thus, delivery …

The Alb3/Oxa1/YidC protein family: membrane-localized chaperones facilitating membrane protein insertion?

A Kuhn, R Stuart, R Henry, RE Dalbey - Trends in cell biology, 2003 - cell.com
Abstract The recently identified Alb3/Oxa1/YidC family constitutes a novel class of proteins
that function in promoting membrane insertion in chloroplasts, mitochondria and bacteria …

A molecular chaperone complex at the lysosomal membrane is required for protein translocation

FA Agarraberes, JF Dice - Journal of cell science, 2001 - journals.biologists.com
A group of cytosolic proteins are targeted to lysosomes for degradation in response to serum
withdrawal or prolonged starvation by a process termed chaperone-mediated autophagy. In …

Oxa1p, an essential component of the N-tail protein export machinery in mitochondria

K Hell, JM Herrmann, E Pratje… - Proceedings of the …, 1998 - National Acad Sciences
A number of nuclear encoded inner membrane proteins of mitochondria span the membrane
in such a manner that their N termini are located in the intermembrane space. Many of these …

Membrane translocation of mitochondrially coded Cox2p: distinct requirements for export of N and C termini and dependence on the conserved protein Oxa1p.

S He, TD Fox - Molecular biology of the cell, 1997 - Am Soc Cell Biol
To study in vivo the export of mitochondrially synthesized protein from the matrix to the
intermembrane space, we have fused a synthetic mitochondrial gene, ARG8m, to the …

[HTML][HTML] Oxa1p mediates the export of the N-and C-termini of pCoxII from the mitochondrial matrix to the intermembrane space

K Hell, J Herrmann, E Pratje, W Neupert, RA Stuart - FEBS letters, 1997 - Elsevier
Oxa1p is a mitochondrial protein reported to be involved in the assembly of the cytochrome
oxidase complex. In the absence of a functional Oxa1p, subunit II of the cytochrome oxidase …

Cox18p Is Required for Export of the Mitochondrially Encoded Saccharomyces cerevisiae Cox2p C-Tail and Interacts with Pnt1p and Mss2p in the Inner Membrane

SA Saracco, TD Fox - Molecular biology of the cell, 2002 - Am Soc Cell Biol
The amino-and carboxy-terminal domains of mitochondrially encoded cytochrome c oxidase
subunit II (Cox2p) are translocated out of the matrix to the intermembrane space. We have …

Biogenesis of cytochrome oxidase—sophisticated assembly lines in the mitochondrial inner membrane

JM Herrmann, S Funes - Gene, 2005 - Elsevier
Biogenesis of the cytochrome oxidase complex in the mitochondrial inner membrane
depends on the concerted action of a variety of proteins. Recent studies shed light on this …

[HTML][HTML] Insertion of proteins into the inner membrane of mitochondria: the role of the Oxa1 complex

RA Stuart - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2002 - Elsevier
The inner mitochondrial membrane harbors a large number of proteins that display a wide
range of topological arrangements. The majority of these proteins are encoded in the cell's …

Knockdown of human Oxa1l impairs the biogenesis of F1Fo-ATP synthase and NADH: ubiquinone oxidoreductase

L Stiburek, D Fornuskova, L Wenchich… - Journal of molecular …, 2007 - Elsevier
The Oxa1 protein is a founding member of the evolutionarily conserved Oxa1/Alb3/YidC
protein family, which is involved in the biogenesis of membrane proteins in mitochondria …