Thyroid dysfunction during gestation and gestational diabetes mellitus: a complex relationship

S Pinto, L Croce, L Carlier, E Cosson… - Journal of …, 2023 - Springer
Purpose Gestational diabetes mellitus (GDM) and thyroid dysfunction during gestation
(GTD) are the two most prevalent endocrinopathies during pregnancy. The aim of the …

Early pregnancy PM2. 5 exposure and its inorganic constituents affect fetal growth by interrupting maternal thyroid function

Y Zhou, Q Zhu, P Wang, J Li, R Luo, W Zhao… - Environmental …, 2022 - Elsevier
Early pregnancy is crucial for fetal growth. Maternal thyroid hormone is critical for fetal
growth and can be disturbed under exogenous exposure. However, it's uncertain whether …

Maternal thyroid hormone programs cardiovascular functions in the offspring

M Pedaran, R Oelkrug, Q Sun, J Resch, L Schomburg… - Thyroid, 2021 - liebertpub.com
Background: Maternal thyroid hormone (TH) plays an essential role for fetal development,
especially for the cardiovascular system and its central control. However, the precise …

Thyroid deficiency before birth alters the adipose transcriptome to promote overgrowth of white adipose tissue and impair thermogenic capacity

SE Harris, MJ De Blasio, X Zhao, M Ma, K Davies… - Thyroid, 2020 - liebertpub.com
Background: Development of adipose tissue before birth is essential for energy storage and
thermoregulation in the neonate and for cardiometabolic health in later life. Thyroid …

NURR1 alterations in perinatal stress: A first step towards late-onset diseases? A narrative review

L Bordoni, I Petracci, J Calleja-Agius, JG Lalor… - Biomedicines, 2020 - mdpi.com
Perinatal life represents a delicate phase of development where stimuli of all sorts, coming
to or from the mother, can influence the programming of the future baby's health. These …

The P300-ARRDC3 axis participates in maternal subclinical hypothyroidism and is involved in abnormal hepatic insulin sensitivity in adult offspring

M Huo, X Yu, X Yuan, J Guo, B Wei, Y Shi, Y Gu… - Heliyon, 2024 - cell.com
Numerous studies have suggested potential associations between maternal subclinical
hypothyroidism (SCH) and adverse metabolic outcomes in offspring, however, the …

Maternal Hypothyroidism in Rats Reduces Placental Lactogen, Lowers Insulin Levels, and Causes Glucose Intolerance

NL Kent, SC Atluri, JSM Cuffe - Endocrinology, 2022 - academic.oup.com
Hypothyroidism increases the incidence of gestational diabetes mellitus (GDM) but the
mechanisms responsible are unknown. This study aimed to assess the pathophysiological …

[HTML][HTML] Association of maternal thyroid disease with obesity in child

KE Lee, HE Oh, SJ Kim, GJ Cho, MJ Oh… - European Journal of …, 2023 - Elsevier
Objectives During pregnancy, many women develop thyroid disorders, which can result in
fetal and neonatal development defects. We investigated whether maternal thyroid …

The joint effect of congenital hypothyroidism and hypercaloric diet consumption as triggers of type 2 diabetes mellitus

JA Tapia-Martínez, M Franco-Colín… - European Thyroid …, 2022 - etj.bioscientifica.com
Introduction Congenital hypothyroidism affects metabolic and thyroid programming, having a
deleterious effect on bodyweight regulation promoting metabolic diseases. This work aimed …

孕期PM2.5暴露致母婴甲状腺功能影响的研究进展

周婧, 张玲, 王琛琛, 吴顺华 - 环境与职业医学, 2023 - jeom.org
环境空气污染已成为普遍存在的全球公共卫生问题, 细颗粒物(PM 2.5) 作为环境空气污染的主要
成分之一, 其直径小, 表面积大, 可以携带各种有毒物质, 通过血气屏障直接进入血液循环 …