Gut bacteria inhabit a complex environment that is shaped by interactions with their host and
the other members of the community. While these ecological interactions have evolved over …

Randomly barcoded transposon mutant libraries are powerful tools for studying gene
function and organization, assessing gene essentiality and pathways, discovering potential …

Global food systems face unprecedented challenges from climate change, extreme weather
events, land and water constraints, biodiversity loss, soil degradation, market volatility, and …

Our ability to predict, control, or design biological function is fundamentally limited by poorly
annotated gene function. This can be particularly challenging in non-model systems …

The human gastrointestinal tract employs an assortment of chemical, enzymatic and immune
barriers to impede pathogen colonization. An essential component of these barriers is the …

Drugs intended to target mammalian cells can have broad off‐target effects on the human
gut microbiota with potential downstream consequences for drug efficacy and side effect …

The creation of green areas within urban centers was born as a response to profoundly
different problems, such as the demographic increase and the progressive urbanization of …

While haplotype‐specific genetic load shapes the evolutionary trajectory of natural and
captive populations, mixed‐haplotype assembly and genotyping hindered its …

Host–microbe interactions are increasingly recognized as important drivers of organismal
health, growth, longevity and community‐scale ecological processes. However, less is …

Regulation of gene expression is a critical link between genotype and phenotype explaining
substantial heritable variation within species. However, we are only beginning to understand …