In the past decade, advances in liquid chromatography‐mass spectrometry (LC‐MS) have
revolutionized untargeted metabolomics analyses. By mining metabolomes more deeply …

Liquid chromatography-mass spectrometry (LC-MS)-based lipidomics has undergone
dramatic developments over the past decade. This review focuses on state of the art in LC …

Chronic inflammation triggers compensatory immunosuppression to stop inflammation and
minimize tissue damage. Studies have demonstrated that endoplasmic reticulum (ER) stress …

METLIN originated as a database to characterize known metabolites and has since
expanded into a technology platform for the identification of known and unknown …

Full-scan, data-dependent acquisition (DDA), and data-independent acquisition (DIA) are
the three common data acquisition modes in high resolution mass spectrometry-based …

Metabolite profiling is critical in many aspects of the life sciences, particularly natural product
research. Obtaining precise information on the chemical composition of complex natural …

The life sciences are currently being transformed by an unprecedented wave of
developments in molecular analysis, which include important advances in instrumental …

When using liquid chromatography/mass spectrometry (LC/MS) to perform untargeted
metabolomics, it is now routine to detect tens of thousands of features from biological …

Bacterial biofilms in the colon alter the host tissue microenvironment. A role for biofilms in
colon cancer metabolism has been suggested but to date has not been evaluated. Using …

It is well established that lactate secreted by fermenting cells can be oxidized or used as a
gluconeogenic substrate by other cells and tissues. It is generally assumed, however, that …