Technological advances in three-dimensional skin tissue engineering

R Cai, N Gimenez-Camino, M Xiao, S Bi… - Reviews on Advanced …, 2023 - degruyter.com
Tissue engineering is an enabling technology that can be used to repair, replace, and
regenerate different types of biological tissues and holds great potential in various …

The importance of the neuro‐immuno‐cutaneous system on human skin equivalent design

SE Vidal Yucha, KA Tamamoto, DL Kaplan - Cell proliferation, 2019 - Wiley Online Library
The skin is a highly complex organ, responsible for sensation, protection against the
environment (pollutants, foreign proteins, infection) and thereby linked to the immune and …

[HTML][HTML] Lipid functions in skin: Differential effects of n-3 polyunsaturated fatty acids on cutaneous ceramides, in a human skin organ culture model

AC Kendall, M Kiezel-Tsugunova… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Ceramides are important for skin health, with a multitude of species found in both dermis
and epidermis. The epidermis contains linoleic acid-Ester-linked Omega-hydroxylated …

Nanoemulsions based on sunflower and rosehip oils: the impact of natural and synthetic stabilizers on skin penetration and an ex vivo wound healing model

CN Pereira Oliveira, M Nani Leite, NA de Paula… - Pharmaceutics, 2023 - mdpi.com
Vegetable oils offer excellent biological properties, but their high lipophilicity limits their
bioavailability. This work aimed to develop nanoemulsions based on sunflower and rosehip …

[HTML][HTML] Bridging the gap between testing and clinics exploring alternative pre-clinical models in melanoma research

J Viegas, B Sarmento - Advanced Drug Delivery Reviews, 2024 - Elsevier
Melanoma, the deadliest form of skin cancer, poses a significant clinical challenge for the
development of effective treatments. Conventional in vivo animal studies have shown limited …

Effects of autologous platelet‑rich plasma injections on facial skin rejuvenation

R Du, T Lei - Experimental and therapeutic medicine, 2020 - spandidos-publications.com
Autologous serum platelet‑rich plasma (PRP) has been used to rejuvenate wrinkled and
aged skin for years; however, the molecular mechanism for the positive effects of PRP on the …

Early Induction of Human Regulatory Dermal Antigen Presenting Cells by Skin-Penetrating Schistosoma Mansoni Cercariae

BMF Winkel, MR Dalenberg, CM De Korne… - Frontiers in …, 2018 - frontiersin.org
Following initial invasion of Schistosoma mansoni cercariae, schistosomula reside in the
skin for several days during which they can interact with the dermal immune system. While …

Treatment of aged wound healing models with FGF2 and ABT‐737 reduces the senescent cell population and increases wound closure rate

U Niyogi, CP Jara, MA Carlson - Wound Repair and …, 2023 - Wiley Online Library
Delayed tissue repair in the aged presents a major socio‐economic and clinical problem.
Age‐associated delay in wound healing can be attributed to multiple factors, including an …

Ex vivo model of human skin (hOSEC) as alternative to animal use for cosmetic tests

TA Andrade, AF Aguiar, FA Guedes, MN Leite… - Procedia …, 2015 - Elsevier
For ethical reasons, the use of experimental animals for skin irritation studies is not desired,
mainly for cosmetical products. Alternative methods for skin irritation testing have been …

Microphysiological systems for the modeling of wound healing and evaluation of pro-healing therapies

HE Deal, AC Brown, MA Daniele - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
Wound healing is a multivariate process involving the coordinated response of numerous
proteins and cell types. Accordingly, biomedical research has seen an increased adoption of …