The landscape of clinical mycology is constantly changing. New therapies for malignant and
autoimmune diseases have led to new risk factors for unusual mycoses. Invasive …

Despite abundant research in the field of antifungal drug discovery, fungal infections remain
a significant healthcare burden. There is an emerging need for the development of novel …

Azole resistance is a concern for the management of diseases caused by Aspergillus
fumigatus in humans. Azole fungicide use in the environment has been identified as a …

The increasing incidence and changing epidemiology of invasive fungal infections continue
to present many challenges to their effective management. The repertoire of antifungal drugs …

Widespread use of azole antifungals in agriculture has been linked to resistance in the
pathogenic fungus Aspergillus fumigatus. We show that exposure of A. fumigatus to the …

Introduction: Therapeutic drug monitoring (TDM) has been shown to optimize the
management of invasive fungal infections (IFIs), particularly for select antifungal agents with …

Opportunistic fungal pathogens can cause a diverse range of diseases in humans. The
increasing rate of fungal infections caused by strains that are resistant to commonly used …

Background Isavuconazole (ISA) is an attractive candidate for primary mold-active
prophylaxis in high-risk patients with hematologic malignancies or hematopoietic cell …

We investigated the prevalence of azole resistance of Aspergillus fumigatus isolates in the
Netherlands by screening clinical A. fumigatus isolates for azole resistance during 2013 …

With increasing frequency, clinical and laboratory-based mycologists are consulted on
invasive fungal diseases caused by rare fungal species. This review aims to give an …