Reference intervals: past, present, and future

K Doyle, DR Bunch - Critical Reviews in Clinical Laboratory …, 2023 - Taylor & Francis
Clinical laboratory test results alone are of little value in diagnosing, treating, and monitoring
health conditions; as such, a clinically actionable cutoff or reference interval is required to …

The origin of ferritin reference intervals: a systematic review

J Truong, K Naveed, D Beriault, D Lightfoot… - The Lancet …, 2024 - thelancet.com
Iron deficiency is a highly prevalent condition, which contributes to unnecessary morbidity,
mortality, and health inequity. A serum ferritin concentration of less than 30 μg/L has a high …

Derivation of sex and age-specific reference intervals for clinical chemistry analytes in healthy Ghanaian adults

SA Bawua, K Ichihara, R Keatley… - Clinical Chemistry and …, 2022 - degruyter.com
Objectvies This study is aimed at establishing reference intervals (RIs) of 40 chemistry and
immunochemistry analytes for Ghanaian adults based on internationally harmonized …

Establishment of reference interval for hemoglobin A1C and other hemoglobin subfractions for healthy Saudi adults

A Borai, K Ichihara, S Bahijri, A Alsofyani, M Elsayid… - Plos one, 2024 - journals.plos.org
Background The establishment of Reference Intervals (RIs) for Hemoglobin A1C and other
hemoglobin subfractions (A1A, A1B, F, LA1C, A0) is of utmost importance in screening …

Establishment of reference intervals for hematological parameters of adult population in the western region of Saudi Arabia

A Borai, K Ichihara, S Bahijri, A Almasoud, W Tamimi… - Plos one, 2023 - journals.plos.org
Background Most of hematology laboratories in Saudi Arabia utilize the reference intervals
(RIs) provided by instrument manufacturers. This study aimed to define RIs of hematological …

Establishment of reference intervals for free light chains and immunoglobulins in Saudi population

A Borai, K Ichihara, W Tamimi, A Masaud… - Clinical Chemistry and …, 2024 - degruyter.com
Objectives Testing of serum-free light chains kappa (κ) and lambda (λ), along with ratio
(FLCR) is essential for the diagnosis and management of monoclonal gammopathies …

[HTML][HTML] The BioRef Infrastructure, a Framework for Real-Time, Federated, Privacy-Preserving, and Personalized Reference Intervals: Design, Development, and …

TU Blatter, H Witte, J Fasquelle-Lopez… - Journal of Medical …, 2023 - jmir.org
Background Reference intervals (RIs) for patient test results are in standard use across
many medical disciplines, allowing physicians to identify measurements indicating …

Region-specific laboratory reference intervals are important: a systematic review of the data from Africa

MA Price, PE Fast, M Mshai, M Lambrick… - PLOS Global Public …, 2022 - journals.plos.org
Region-specific laboratory reference intervals (RIs) are important for clinical trials and these
data are often sparse in priority areas for research, including Africa. We reviewed data on …

Ferritin and its association with anaemia in a healthy adult population in Kenya

G Omuse, A Chege, DE Kawalya, E Kagotho, D Maina - Plos one, 2022 - journals.plos.org
Background Iron deficiency is the commonest cause of anaemia worldwide. Serum ferritin is
the most sensitive non-invasive indicator of iron stores but its utility is compromised in …

An indirect approach for reference intervals establishment of immunoglobulin A, G and M: the combination of laboratory database and statistics

J Chai, Z Sun, S Zhang, Q Zhou, J Xu - Scandinavian Journal of …, 2022 - Taylor & Francis
Immunoglobulins are affected by sex, age and region, so it is necessary to establish suitable
reference intervals (RIs) for clinical diagnosis. Various statistical methods were used to …