This review traces current applications of the residence time theory in various solid unit
operations. Besides reviewing recent experimental and simulation studies in the literature …

Blend uniformity is a critical quality attribute in continuous pharmaceutical manufacturing.
However, its measurement is challenging due to the difficulty and inaccessibility of sampling …

Manufacturing of powder-based products is a focus of increasing research in the recent
years. The main reason is the lack of predictive process models connecting process …

Continuous manufacturing has attracted increasing research attention in the pharmaceutical
industry within the last decade. Based on the extensive experimental studies, numerous …

Abstract Positron Emission Particle Tracking (PEPT) is a non-invasive measurement
technique which offers the ability to track the motion of individual particles with high temporal …

This study is concerned with the development of a novel population balance model (PBM)
framework that can qualitatively capture the dynamics of a continuous powder mixing …

It has been recognized that the application of quality by design (QbD) to continuous
processing in the pharmaceutical industry leads to better process control, improved product …

While continuous powder mixing has been an area of active research in recent years, effects
of operating conditions on the mixing performance has not been well understood yet. Based …

This paper describes the development of a multidimensional population balance model
(PBM) which can account for the dynamics of a continuous powder mixing/blending process …

The present study summarizes the experimental characterization of a new continuous
powder mixer (GCG-70 by Glatt®) using common pharmaceutical ingredients. The powder …