Biological roles of adenine methylation in RNA
K Boulias, EL Greer - Nature Reviews Genetics, 2023 - nature.com
Abstract N 6-Methyladenosine (m6A) is one of the most abundant modifications of the
epitranscriptome and is found in cellular RNAs across all kingdoms of life. Advances in …
epitranscriptome and is found in cellular RNAs across all kingdoms of life. Advances in …
The role of m6A modification in the biological functions and diseases
X Jiang, B Liu, Z Nie, L Duan, Q Xiong, Z Jin… - Signal transduction and …, 2021 - nature.com
Abstract N6-methyladenosine (m6A) is the most prevalent, abundant and conserved internal
cotranscriptional modification in eukaryotic RNAs, especially within higher eukaryotic cells …
cotranscriptional modification in eukaryotic RNAs, especially within higher eukaryotic cells …
Epigenetic regulation in the tumor microenvironment: molecular mechanisms and therapeutic targets
J Yang, J Xu, W Wang, B Zhang, X Yu… - Signal transduction and …, 2023 - nature.com
Over decades, researchers have focused on the epigenetic control of DNA-templated
processes. Histone modification, DNA methylation, chromatin remodeling, RNA modification …
processes. Histone modification, DNA methylation, chromatin remodeling, RNA modification …
The role of m6A, m5C and Ψ RNA modifications in cancer: Novel therapeutic opportunities
RNA modifications have recently emerged as critical posttranscriptional regulators of gene
expression programmes. Significant advances have been made in understanding the …
expression programmes. Significant advances have been made in understanding the …
m6A modification in coding and non-coding RNAs: roles and therapeutic implications in cancer
N 6-Methyladenosine (m 6 A) RNA modification has emerged in recent years as a new layer
of regulatory mechanism controlling gene expression in eukaryotes. As a reversible …
of regulatory mechanism controlling gene expression in eukaryotes. As a reversible …
Roles of METTL3 in cancer: mechanisms and therapeutic targeting
C Zeng, W Huang, Y Li, H Weng - Journal of hematology & oncology, 2020 - Springer
Abstract N 6-methyladenosine (m 6 A) is the most abundant mRNA modification and is
catalyzed by the methyltransferase complex, in which methyltransferase-like 3 (METTL3) is …
catalyzed by the methyltransferase complex, in which methyltransferase-like 3 (METTL3) is …
[HTML][HTML] The role of m6A RNA methylation in cancer
T Sun, R Wu, L Ming - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Abstract N6-methyladenosine (m6A), the most abundant internal modification of RNA in
eukaryotic cells, has gained increasing attention in recent years. The m6A modification …
eukaryotic cells, has gained increasing attention in recent years. The m6A modification …
The Critical Role of RNA m6A Methylation in Cancer
Since the identification of the first RNA demethylase and the establishment of methylated
RNA immunoprecipitation-sequencing methodology 6 to 7 years ago, RNA methylation has …
RNA immunoprecipitation-sequencing methodology 6 to 7 years ago, RNA methylation has …
Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism
Abstract N 6-methyladenosine (m6A) is a chemical modification present in multiple RNA
species, being most abundant in mRNAs. Studies on enzymes or factors that catalyze …
species, being most abundant in mRNAs. Studies on enzymes or factors that catalyze …
YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA
Abstract N 6-methyladenosine (m 6 A) is the most abundant internal modification in
eukaryotic messenger RNAs (mRNAs), and plays important roles in cell differentiation and …
eukaryotic messenger RNAs (mRNAs), and plays important roles in cell differentiation and …