Radiotheranostics in oncology: making precision medicine possible

EO Aboagye, TD Barwick… - CA: a cancer journal for …, 2023 - Wiley Online Library
A quintessential setting for precision medicine, theranostics refers to a rapidly evolving field
of medicine in which disease is diagnosed followed by treatment of disease‐positive …

Hybrid total-body pet scanners—current status and future perspectives

V Nadig, K Herrmann, FM Mottaghy… - European journal of …, 2022 - Springer
Purpose Since the 1990s, PET has been successfully combined with MR or CT systems. In
the past years, especially PET systems have seen a trend towards an enlarged axial field of …

Performance characteristics of the Biograph Vision Quadra PET/CT system with a long axial field of view using the NEMA NU 2-2018 standard

GA Prenosil, H Sari, M Fürstner… - Journal of nuclear …, 2022 - Soc Nuclear Med
Our purpose was to evaluate the performance of the Biograph Vision Quadra PET/CT
system. This new system is based on the Biograph Vision 600, using the same silicon …

Positronium imaging with the novel multiphoton PET scanner

P Moskal, K Dulski, N Chug, C Curceanu… - Science …, 2021 - science.org
In vivo assessment of cancer and precise location of altered tissues at initial stages of
molecular disorders are important diagnostic challenges. Positronium is copiously formed in …

First results on kinetic modelling and parametric imaging of dynamic 18F-FDG datasets from a long axial FOV PET scanner in oncological patients

H Sari, C Mingels, I Alberts, J Hu, D Buesser… - European journal of …, 2022 - Springer
Purpose To investigate the kinetics of 18 F-fluorodeoxyglucose (18 F-FDG) by positron
emission tomography (PET) in multiple organs and test the feasibility of total-body …

Long axial field of view PET scanners: a road map to implementation and new possibilities

RHJA Slart, C Tsoumpas, AWJM Glaudemans… - European journal of …, 2021 - Springer
In this contribution, several opportunities and challenges for long axial field of view (LAFOV)
PET are described. It is an anthology in which the main issues have been highlighted. A …

Using domain knowledge for robust and generalizable deep learning-based CT-free PET attenuation and scatter correction

R Guo, S Xue, J Hu, H Sari, C Mingels… - Nature …, 2022 - nature.com
Despite the potential of deep learning (DL)-based methods in substituting CT-based PET
attenuation and scatter correction for CT-free PET imaging, a critical bottleneck is their …

Total-body PET multiparametric imaging of cancer using a voxelwise strategy of compartmental modeling

G Wang, L Nardo, M Parikh… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Quantitative dynamic PET with compartmental modeling has the potential to enable
multiparametric imaging and more accurate quantification than static PET imaging …

Long-axial field-of-view PET/CT: perspectives and review of a revolutionary development in nuclear medicine based on clinical experience in over 7000 patients

I Alberts, H Sari, C Mingels, A Afshar-Oromieh, T Pyka… - Cancer Imaging, 2023 - Springer
Recently introduced long-axial field-of-view (LAFOV) PET/CT systems represent one of the
most significant advancements in nuclear medicine since the advent of multi-modality …

Application of the long axial field-of-view PET/CT with low-dose [18F]FDG in melanoma

C Sachpekidis, L Pan, A Kopp-Schneider… - European Journal of …, 2023 - Springer
Aim The recent introduction of long axial field-of-view (LAFOV) PET/CT scanners has
yielded very promising results regarding image quality and sensitivity in oncological …