Chronic kidney disease (CKD) is a relentlessly progressive disease with a very high
mortality mainly due to cardiovascular complications. Endothelial dysfunction is well …

Over the last decades, childhood and adolescence have emerged as an important window
of opportunity to prevent atherosclerotic cardiovascular disease (ASCVD) later in life. Here …

Chronic kidney disease (CKD) can be defined as a sustained damage of the renal
parenchyma leading to chronic deterioration of renal function that may gradually progress to …

In children with chronic kidney disease (CKD), optimal control of bone and mineral
homeostasis is essential, not only for the prevention of debilitating skeletal complications …

Background CKD is characterized by a sustained proinflammatory response of the immune
system, promoting hypertension and cardiovascular disease. The underlying mechanisms …

The lifespan of children with advanced chronic kidney disease (CKD), although improved
over the past 2 decades, remains low compared with the general pediatric population …

Mineral and bone disorders (MBD) are common in patients with chronic kidney disease
(CKD), contributing to significant morbidity and mortality. For several decades, the first-line …

Chronic dialysis is rarely required during childhood. Despite technical advances that have
facilitated the treatment of even the youngest children, morbidity and mortality remain higher …

Background Hypertension and cardiovascular disease are common in children undergoing
dialysis. Studies suggest that hemodiafiltration (HDF) may reduce cardiovascular mortality in …

Mineral and bone disorder (MBD) is widely prevalent in children with chronic kidney disease
(CKD) and is associated with significant morbidity. CKD may cause disturbances in bone …