Spinal cord injury (SCI) represents one of the most complicated and heterogeneous
pathological processes of central nervous system (CNS) impairments, which is still beyond …

Facioscapulohumeral muscular dystrophy (FSHD) is a debilitating muscular dystrophy with a
variable age of onset, severity, and progression. While there is still no cure for this disease …

Constitutive nuclear factor κB (NF-κB) activation is a hallmark of colon tumor growth. Cyclin-
dependent kinases (CDKs) are critical cell-cycle regulators, and inhibition of CDK activity …

Facioscapulohumeral muscular dystrophy is a slowly progressive but devastating myopathy
caused by loss of repression of the transcription factor DUX4; however, DUX4 expression is …

Aberrant expression of the transcription factor DUX4 from D4Z4 macrosatellite repeats on
chromosome 4q35, and its transcriptome, associate with pathogenesis in …

Skin is the body barrier that constrains the infiltration of particles and exogenous aggression,
in which the hair follicle plays an important role. Recent studies have shown that small …

Facioscapulohumeral muscular dystrophy (FSHD) is linked to epigenetic derepression of the
germline/embryonic transcription factor DUX4 in skeletal muscle. However, the etiology of …

Translocations producing rearranged versions of the transcription factor double homeobox 4
(DUX4-r) are one of the most frequent causes of B cell acute lymphoblastic leukemia (B …

Recent efforts reclassified B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) into
more refined subtypes. Nevertheless, outcomes of relapsed BCP-ALL remain unsatisfactory …

Background We have previously demonstrated that double homeobox 4 centromeric
(DUX4C) encoded for a functional DUX4c protein upregulated in dystrophic skeletal …