Harnessing the power of miRNAs: the molecular architects of asthma pathogenesis and potential targets for therapeutic innovation

TM Al-Noshokaty, D Fathi, AI Abulsoud… - … -Research and Practice, 2023 - Elsevier
Asthma is a chronic non-communicable respiratory disease that is characterized by airway
inflammation and hyperreactivity. Defective functions of airway smooth muscle and …

Emerging role of MicroRNAs and long noncoding RNAs in respiratory disease

R Booton, MA Lindsay - Chest, 2014 - Elsevier
The advent of techniques such as microarrays and high-throughput sequencing has
revolutionized our ability to examine messenger RNA (mRNA) expression within the …

Serum microRNA expression signatures identified from genome‐wide microRNA profiling serve as novel noninvasive biomarkers for diagnosis and recurrence of …

X Jiang, L Du, L Wang, J Li, Y Liu… - … journal of cancer, 2015 - Wiley Online Library
Recent advantages of serum microRNAs (miRNAs) open a new realm of possibilities for
noninvasive diagnosis and prognosis of bladder cancer (BC). The aim of our study was to …

Small non-coding RNAs in human cancer

Q Xiong, Y Zhang, J Li, Q Zhu - Genes, 2022 - mdpi.com
Small non-coding RNAs are widespread in the biological world and have been extensively
explored over the past decades. Their fundamental roles in human health and disease are …

Early events in the molecular pathogenesis of lung cancer

H Kadara, P Scheet, II Wistuba, AE Spira - Cancer prevention research, 2016 - AACR
The majority of cancer-related deaths in the United States and worldwide are attributed to
lung cancer. There are more than 90 million smokers in the United States who represent a …

The impact of microRNA-mediated PI3K/AKT signaling on epithelial-mesenchymal transition and cancer stemness in endometrial cancer

P Dong, Y Konno, H Watari, M Hosaka… - Journal of translational …, 2014 - Springer
Activation of the PI3K/AKT pathway, a common mechanism in all subtypes of endometrial
cancers (endometrioid and non-endometrioid tumors), has important roles in contributing to …

miR-199a-5p and miR-495 target GRP78 within UPR pathway of lung cancer

A Ahmadi, B Khansarinejad, S Hosseinkhani… - Gene, 2017 - Elsevier
Introduction Non-small cell lung cancer (NSCLC) is the most common subtype of lung
cancer. One of the signal transduction pathways related to NSCLC is Unfolded Protein …

Epigenetics in idiopathic pulmonary fibrosis

A Tzouvelekis, N Kaminski - Biochemistry and Cell Biology, 2015 - cdnsciencepub.com
Idiopathic pulmonary fibrosis (IPF) is a lethal chronic lung disorder with no effective
treatment and a prognosis worse than that of lung cancer. Despite extensive research …

[HTML][HTML] Characterization of microRNA transcriptome in lung cancer by next-generation deep sequencing

J Ma, K Mannoor, L Gao, A Tan, MA Guarnera… - Molecular …, 2014 - Elsevier
Non-small cell lung cancer (NSCLC) is the leading cause of cancer death. Systematically
characterizing miRNAs in NSCLC will help develop biomarkers for its diagnosis and …

[HTML][HTML] BCR-ABL1 mediated miR-150 downregulation through MYC contributed to myeloid differentiation block and drug resistance in chronic myeloid leukemia

K Srutova, N Curik, P Burda, F Savvulidi… - …, 2018 - ncbi.nlm.nih.gov
The fusion oncoprotein BCR-ABL1 exhibits aberrant tyrosine kinase activity and it has been
proposed that it deregulates signaling networks involving both transcription factors and non …