Circular RNAs as the pivotal regulators of epithelial-mesenchymal transition in gastrointestinal tumor cells

RA Mahmoudian, I Akhlaghipour, M Lotfi… - … -Research and Practice, 2023 - Elsevier
Gastrointestinal (GI) cancers, as the most common human malignancies are always
considered one of the most important health challenges in the world. Late diagnosis in …

circ‐SIRT1 Promotes Colorectal Cancer Proliferation and EMT by Recruiting and Binding to eIF4A3

X Wang, S Liu, B Xu, Y Liu, P Kong… - Analytical Cellular …, 2021 - Wiley Online Library
Circular RNA (circRNA), a recently identified type of endogenous noncoding RNA, has been
implicated in the occurrence and development of a variety of tumors; however, whether circ …

[HTML][HTML] Role of sirtuins in esophageal cancer: Current status and future prospects

R Otsuka, K Hayano, H Matsubara - World Journal of …, 2022 - ncbi.nlm.nih.gov
Esophageal cancer (EC) is a malignant cancer that still has a poor prognosis, although its
prognosis has been improving with the development of multidisciplinary treatment …

Interception of signaling circuits of esophageal adenocarcinoma cells by resveratrol reveals molecular and immunomodulatory signatures

H Dhir, M Choudhury, K Patil, C Cheung, A Bodlak… - Cancers, 2021 - mdpi.com
Simple Summary Adenocarcinoma of the esophagus has been on the rise lately. Increase in
mortality due to a paucity of efficacious drugs for this cancer prompted us to discover …

Casticin impacts key signaling pathways in colorectal cancer cells leading to cell death with therapeutic implications

M Kowalski, A Assa, K Patil, C Terrell, N Holliday… - Genes, 2022 - mdpi.com
Colorectal cancer is the third most frequently encountered cancer worldwide. While current
chemotherapeutics help to manage the disease to some extent, they have eluded achieving …

Disruption of Glioblastoma Multiforme Cell Circuits with Cinnamaldehyde Highlights Potential Targets with Implications for Novel Therapeutic Strategies

S Srivastava, K Patil, EW Thompson, SA Nakhai… - Cells, 2023 - mdpi.com
Glioblastoma multiforme (GBM) is a major aggressive primary brain tumor with dismal
survival outcome and few therapeutic options. Although Temozolomide (TMZ) is a part of the …

[PDF][PDF] A transformação maligna no câncer de esôfago: Aspectos moleculares/Malignant transformation in esophageal cancer: Molecular aspects

GC Machado, JL De Morais, ND Carvalho… - Brazilian Journal of …, 2021 - researchgate.net
Introdução: O câncer de esôfago (CE) é uma afecção complexa, multifatorial e associada a
uma elevada taxa de morbimortalidade. Os dois principais tipos são, adenocarcinoma e …

Disruption of Colorectal cancer network by polyphyllins reveals pivotal entities with implications for chemoimmunotherapy

R Siripuram, Z Bartolek, K Patil, SS Gill, SB Pai - Biomedicines, 2022 - mdpi.com
The prevalence of colorectal cancer has increased world-wide with high rates of mortality
and morbidity. In the absence of efficacious drugs to treat this neoplasia, there is an …

[PDF][PDF] WIP: A novel problem-driven learning laboratory course in which biomedical engineering students conduct experiments of their own design to answer an …

B Pai, K Patil, T Fernandez, P Benkeser… - 2022 ASEE Annual …, 2022 - peer.asee.org
Often, in traditional laboratory courses, students carry out “experiments” for which the results
are already known, following protocols that they are expected to perform as written. Using …

Progress in Biomaterials for Application of Esophageal Stents

Y Hou, J Li, A Yasin, M Iqbal - Biomaterials and Materials for …, 2021 - taylorfrancis.com
Esophageal cancer is a malignant tumor of the digestive tract in esophageal epithelial
tissue, which is highly difficult to cure globally and has a high mortality ratio (10%–15 …