MicroRNAs contribute to breast cancer invasiveness
I Fridrichova, I Zmetakova - Cells, 2019 - mdpi.com
Cancer statistics in 2018 highlight an 8.6 million incidence in female cancers, and 4.2 million
cancer deaths globally. Moreover, breast cancer is the most frequent malignancy in females …
cancer deaths globally. Moreover, breast cancer is the most frequent malignancy in females …
Isomirs–hidden soldiers in the mirna regulatory army, and how to find them?
I Glogovitis, G Yahubyan, T Würdinger… - Biomolecules, 2020 - mdpi.com
Numerous studies on microRNAs (miRNA) in cancer and other diseases have been
accompanied by diverse computational approaches and experimental methods to predict …
accompanied by diverse computational approaches and experimental methods to predict …
[HTML][HTML] IsomiR expression profiles in human lymphoblastoid cell lines exhibit population and gender dependencies
P Loher, ER Londin, I Rigoutsos - Oncotarget, 2014 - ncbi.nlm.nih.gov
For many years it was believed that each mature microRNA (miRNA) existed as a single
entity with fixed endpoints and a 'static'and unchangeable primary sequence. However …
entity with fixed endpoints and a 'static'and unchangeable primary sequence. However …
Naturally existing isoforms of miR-222 have distinct functions
F Yu, KA Pillman, CT Neilsen, J Toubia… - Nucleic acids …, 2017 - academic.oup.com
Deep-sequencing reveals extensive variation in the sequence of endogenously expressed
microRNAs (termed 'isomiRs') in human cell lines and tissues, especially in relation to the …
microRNAs (termed 'isomiRs') in human cell lines and tissues, especially in relation to the …
Bacterial infection drives the expression dynamics of microRNAs and their isomiRs
KJ Siddle, L Tailleux, M Deschamps, YHE Loh… - PLoS …, 2015 - journals.plos.org
The optimal coordination of the transcriptional response of host cells to infection is essential
for establishing appropriate immunological outcomes. In this context, the role of microRNAs …
for establishing appropriate immunological outcomes. In this context, the role of microRNAs …
IsomiR Bank: a research resource for tracking IsomiRs
Next-Generation Sequencing (NGS) technology has revealed that microRNAs (miRNAs) are
capable of exhibiting frequent differences from their corresponding mature reference …
capable of exhibiting frequent differences from their corresponding mature reference …
QuickMIRSeq: a pipeline for quick and accurate quantification of both known miRNAs and isomiRs by jointly processing multiple samples from microRNA sequencing
Background Genome-wide miRNA expression data can be used to study miRNA
dysregulation comprehensively. Although many open-source tools for microRNA (miRNA) …
dysregulation comprehensively. Although many open-source tools for microRNA (miRNA) …
A novel miR-451a isomiR, associated with amelanotypic phenotype, acts as a tumor suppressor in melanoma by retarding cell migration and invasion
S Babapoor, E Fleming, R Wu, SS Dadras - PloS one, 2014 - journals.plos.org
miRNAs are key regulatory small non-coding RNAs involved in critical steps of melanoma
tumorigenesis; however, the relationship between sequence specific variations at the 5′ or …
tumorigenesis; however, the relationship between sequence specific variations at the 5′ or …
Regulation of miRNA processing and miRNA mediated gene repression in cancer
S Bajan, G Hutvagner - Microrna, 2014 - ingentaconnect.com
The majority of human protein-coding genes are predicted to be targets of miRNA-mediated
posttranscriptional regulation. The widespread influence of miRNAs is illustrated by their …
posttranscriptional regulation. The widespread influence of miRNAs is illustrated by their …
DeAnnIso: a tool for online detection and annotation of isomiRs from small RNA sequencing data
Abstract Small RNA (sRNA) Sequencing technology has revealed that microRNAs (miRNAs)
are capable of exhibiting frequent variations from their canonical sequences, generating …
are capable of exhibiting frequent variations from their canonical sequences, generating …