Abstract Neuroimaging using the 7-Tesla (7T) human magnetic resonance (MR) system is
rapidly gaining popularity after being approved for clinical use in the European Union and …

Glutamate is the primary excitatory neurotransmitter in the mammalian central nervous
system. As such, its proper regulation is essential to the healthy function of the human brain …

Temporal lobe epilepsy (TLE) is one of the most common subtypes of focal epilepsy, with
mesial temporal sclerosis (MTS) being a common radiological and histopathological finding …

Since the inception of CEST MRI in the 1990s, a number of compounds have been identified
as suitable for generating contrast, including paramagnetic lanthanide complexes …

Purpose To develop a CEST quantification model to map glutamate concentration in the
mouse brain at 11.7 T, overcoming the limitations of conventional glutamate‐weighted CEST …

Improved structural MRI increases detection of abnormalities that may underlie epilepsy.
Diffusion, structural and functional MRI indicate the widespread associations of epilepsy …

Purpose Proton exchange rate (K ex) is a valuable biophysical metric. K ex MRI may
augment conventional structural MRI by revealing brain impairments at the molecular level …

Multimodal imaging plays an important role in epilepsy evaluation to localize the source of
seizures and is crucial for successful surgical intervention in drug-resistant cases. Up to one …

Chemical exchange saturation transfer (CEST) MRI can detect diluted molecules, ie,
metabolites and proteins, with enhanced sensitivity due to the exchange between their …

L'imagerie par résonance magnétique du transfert de saturation par échange chimique (IRM
CEST) représente un outil puissant pour l'étude du métabolisme, offrant une résolution …