Significance: Oxidative stress represents the common hallmark of pathological conditions
associated with cardiovascular disease (CVD), including atherosclerosis, heart failure …

Stachydrine is extracted from the leaves of Leonurus japonicus Houtt (or Motherwort,“Yi Mu
Cao” in Traditional Chinese Medicine) and is the major bioactive ingredient. So far …

Objectives We recently identified a health conscious food pattern (HCFP) associated with
reduced risk of cardiometabolic disease. However, the molecular events linking the healthy …

Leonurus japonicus Houtt. is a traditional medicinal herb with significant effects; dating back
more than 1800 years, it is widely used in Asia. In traditional Chinese medicine, it is …

Ergothioneine (Egt), the betaine of 2-mercapto-L-histidine, is a dietary antioxidant protecting
against many diseases, including cardiovascular disease (CVD), through a redox …

Plants belonging to the genus Leonurus, also named motherwort, are traditionally used for
anti-gynecological disorder in East Asia, and for sedative in Europe. Chemical investigation …

Primary percutaneous coronary intervention (PPCI) is a pivotal treatment in ST‐segment
elevation myocardial infarction (STEMI) patients. However, in hyperglycemic‐STEMI …

Stachydrine, a constituent of Leonurus japonicus Houtt which also called Japanese
motherwort has been shown to improve vascular microcirculation and ameliorate …

Abstract Silent information regulator-2 (Sir-2) proteins, or sirtuins, are a highly conserved
protein family of histone deacetylases that promote longevity by mediating many of the …

Background: Sirtuin1 is an epigenetic enzyme involved in histone and nonhistone protein
deacetylation. It acts primarily as a metabolic sensor, which responses to changing energy …