Hereditary colorectal polyposis and cancer syndromes: a primer on diagnosis and management

P Kanth, J Grimmett, M Champine, R Burt… - Official journal of the …, 2017 - journals.lww.com
Colorectal cancer (CRC) is the fourth most common cancer amongst men and women.
Between 3 and 6% of all CRCs are attributed to well-defined inherited syndromes, including …

[HTML][HTML] An update on the morphology and molecular pathology of serrated colorectal polyps and associated carcinomas

RK Pai, M Bettington, A Srivastava, C Rosty - Modern Pathology, 2019 - Elsevier
Our understanding of serrated colorectal polyps has increased dramatically over the past
two decades and has led to a modern classification scheme for these lesions. Sessile …

Advanced imaging for detection and differentiation of colorectal neoplasia: European Society of Gastrointestinal Endoscopy (ESGE) Guideline–Update 2019

R Bisschops, JE East, C Hassan, Y Hazewinkel… - …, 2019 - thieme-connect.com
1 ESGE suggests that high definition endoscopy, and dye or virtual chromoendoscopy, as
well as add-on devices, can be used in average risk patients to increase the endoscopist's …

Detection rate of serrated polyps and serrated polyposis syndrome in colorectal cancer screening cohorts: a European overview

JEG IJspeert, R Bevan, C Senore, MF Kaminski… - Gut, 2017 - gut.bmj.com
Objective The role of serrated polyps (SPs) as colorectal cancer precursor is increasingly
recognised. However, the true prevalence SPs is largely unknown. We aimed to evaluate …

Serrated polyps of the large intestine: current understanding of diagnosis, pathogenesis, and clinical management

C Rosty, DG Hewett, IS Brown, BA Leggett… - Journal of …, 2013 - Springer
Approximately 30% of colorectal carcinomas develop via the serrated neoplasia pathway
characterized by widespread DNA methylation and frequent BRAF mutation. Serrated …

CT-colonography vs. colonoscopy for detection of high-risk sessile serrated polyps

JEG IJspeert, CJT Nolthenius, EJ Kuipers… - Official journal of the …, 2016 - journals.lww.com
Objectives: Sessile serrated polyps (SSPs) are suggested to be the precursors of 15–30% of
all colorectal cancers (CRCs). Therefore, CRC screening modalities should also be …

Serrated colon polyps as precursors to colorectal cancer

S Sweetser, TC Smyrk, FA Sinicrope - Clinical Gastroenterology and …, 2013 - Elsevier
Identification of the serrated neoplasia pathway has improved our understanding of the
pathogenesis of colorectal cancer (CRC). Insights include an increased recognition of the …

Sessile serrated adenomas: an evidence-based guide to management

SD Crockett, DC Snover, DJ Ahnen, JA Baron - Clinical Gastroenterology …, 2015 - Elsevier
The concept of serrated colorectal neoplasia and a serrated pathway to colorectal cancer
(CRC) is relatively new and continuing to evolve, but it has become highly relevant to …

Serrated polyposis syndrome

G Mankaney, C Rouphael, CA Burke - Clinical Gastroenterology and …, 2020 - cghjournal.org
Colorectal serrated polyps (SPs) are a pathologi-cally diverse group of lesions that include
hyperplastic polyps (HPs), traditional serrated adenomas (TSAs), and sessile serrated …

Reassessment colonoscopy to diagnose serrated polyposis syndrome in a colorectal cancer screening population

L Rivero-Sanchez, M Lopez-Ceron, S Carballal… - …, 2017 - thieme-connect.com
Background and study aims Serrated polyposis syndrome (SPS) is a high risk condition for
colorectal cancer (CRC). Surveillance strategies for patients with serrated lesions remain …