[HTML][HTML] Necrotic enteritis in broiler chickens: disease characteristics and prevention using organic antibiotic alternatives–a comprehensive review

ME Abd El-Hack, MT El-Saadony, AR Elbestawy… - Poultry science, 2022 - Elsevier
In line with the substantial increase in the broiler industry worldwide, Clostridium perfringens-
induced necrotic enteritis (NE) became a continuous challenge leading to high economic …

Expansion of the Clostridium perfringens toxin-based typing scheme

JI Rood, V Adams, J Lacey, D Lyras, BA McClane… - Anaerobe, 2018 - Elsevier
Clostridium perfringens causes many different histotoxic and enterotoxic diseases in
humans and animals as a result of its ability to produce potent protein toxins, many of which …

Pathogenicity and virulence of Clostridium perfringens

I Mehdizadeh Gohari, M A. Navarro, J Li, A Shrestha… - Virulence, 2021 - Taylor & Francis
Clostridium perfringens is an extremely versatile pathogen of humans and livestock, causing
wound infections like gas gangrene (clostridial myonecrosis), enteritis/enterocolitis …

Towards an Understanding of the Role of Clostridium Perfringens Toxins in Human and Animal Disease

FA Uzal, JC Freedman, A Shrestha, JR Theoret… - Future …, 2014 - Taylor & Francis
Clostridium perfringens uses its arsenal of> 16 toxins to cause histotoxic and intestinal
infections in humans and animals. It has been unclear why this bacterium produces so many …

[HTML][HTML] Review of paper-based microfluidic analytical devices for in-field testing of pathogens

W Li, X Ma, YC Yong, G Liu, Z Yang - Analytica Chimica Acta, 2023 - Elsevier
Pathogens cause various infectious diseases and high morbidity and mortality which is a
global public health threat. The highly sensitive and specific detection is of significant …

Mechanisms of Action and Cell Death Associated with Clostridium perfringens Toxins

MA Navarro, BA McClane, FA Uzal - Toxins, 2018 - mdpi.com
Clostridium perfringens uses its large arsenal of protein toxins to produce histotoxic,
neurologic and intestinal infections in humans and animals. The major toxins involved in …

Epsilon toxin–producing Clostridium perfringens colonize the multiple sclerosis gut microbiome overcoming CNS immune privilege

Y Ma, D Sannino, JR Linden, S Haigh… - The Journal of …, 2023 - Am Soc Clin Investig
Multiple sclerosis (MS) is a complex disease of the CNS thought to require an environmental
trigger. Gut dysbiosis is common in MS, but specific causative species are unknown. To …

Isolation of Clostridium perfringens Type B in an Individual at First Clinical Presentation of Multiple Sclerosis Provides Clues for Environmental Triggers of the …

KR Rumah, J Linden, VA Fischetti, T Vartanian - PloS one, 2013 - journals.plos.org
We have isolated Clostridium perfringens type B, an epsilon toxin-secreting bacillus, from a
young woman at clinical presentation of Multiple Sclerosis (MS) with actively enhancing …

Comparative pathogenesis of enteric clostridial infections in humans and animals

FA Uzal, MA Navarro, J Li, JC Freedman, A Shrestha… - Anaerobe, 2018 - Elsevier
Several enteric clostridial diseases can affect humans and animals. Of these, the enteric
infections caused by Clostridium perfringens and Clostridium difficile are amongst the most …

Clostridium perfringens—Opportunistic Foodborne Pathogen, Its Diversity and Epidemiological Significance

T Grenda, A Jarosz, M Sapała, A Grenda, E Patyra… - Pathogens, 2023 - mdpi.com
The C. perfringens species is associated with various environments, such as soils, sewage,
and food. However, it is also a component of the gastrointestinal (GI) microflora (ie …