[HTML][HTML] Chromatographic methods for the simultaneous determination of binary mixture of Saxagliptin HCl and Metformin HCl

HA Merey, NK Ramadan, SS Diab… - Bulletin of faculty of …, 2017 - Elsevier
Two chromatographic methods were suggested for the simultaneous determination of a
binary mixture containing Saxagliptin HCl (SAG) and Metformin HCl (MET). First method was …

Development and validation of rp-hplc method for the simultaneous estimation of linagliptin, empagliflozin and metformin in solid dosage forms

T Kiran, P Parvathi, JN Kumar - Asian Journal of Pharmaceutical …, 2020 - indianjournals.com
The purpose of the investigation was to develop a simple, rapid and accurate RP-HPLC
method to determine assay of Linagliptin, Empagliflozin and Metformin in solid dosage …

[PDF][PDF] Determination of alogliptin benzoate and metformin hydrochloride in tablet dosage form by simultaneous equation and absorption ratio method

DB Sen, AK Sen, A Zanwar, R Balaraman, A Seth - 2015 - researchgate.net
Objective: Development and validation of two simple, rapid, accurate and sensitive UV-
spectrophotometric methods for simultaneous estimation of alogliptin benzoate (ALO) and …

Comparative study between UHPLC-UV and UPLC-MS/MS methods for determination of alogliptin and metformin in their pharmaceutical combination

S Mowaka, BM Ayoub - Die Pharmazie-An International Journal …, 2017 - ingentaconnect.com
A new UPLC-MS/MS method (method A), for simultaneous determination of alogliptin (ALN)
and metformin (MET) in their recently approved pharmaceutical combination Kazano® …

[PDF][PDF] New validated stability indicating RP-HPLC method for simultaneous estimation of metformin and alogliptin in human plasma

KS Ashutosh, D Manidipa… - J Chromatogr Sep …, 2015 - pdfs.semanticscholar.org
A validated new stability indicating RP-HPLC method for the quantitative determination of
metformin and alogliptin in human plasma was developed as per US-FDA guidelines. The …

Smart spectrophotometric methods based on normalized spectra for simultaneous determination of alogliptin and metformin in their combined tablets

NT Lamie, MA Mahrouse - Spectrochimica Acta Part A: Molecular and …, 2018 - Elsevier
Alogliptin (ALO) and metformin (MET) are coformulated for the treatment of type II diabetes
mellitus. ALO is estimated at its λ max 277 nm (0 D), while MET was determined accurately …

A guide for using experimental design in chromatographic method development: Applied to the analysis of selected anti-diabetic pharmaceutical combinations

BM Ayoub, O Abdel-Aziz - Die Pharmazie-An International …, 2016 - ingentaconnect.com
A guide experimental design in chromatographic method development was described and
applied successfully to the analysis of different recently approved anti-diabetic …

[PDF][PDF] Simultaneous HPTLC analysis of gliclazide and metformin hydrochloride in bulk and tablet dosage form

V Patil, S Kale, P Sahare, S Vithaldas - Journal of Scientific and Innovative …, 2014 - Citeseer
This paper presents the development and validation of high performance thin layer
chromatography (HPTLC) with a densiotometric detection method for the simultaneous …

Isolation and characterization of related substances in alogliptin benzoate by LC-QTOF mass spectrometric techniques

Y Lu, D Yang, Z Li, T Hang, M Song - Journal of Pharmaceutical and …, 2016 - Elsevier
A highly specific and efficient LC-QTOF mass spectrometric method was developed for the
separation and characterization of process related substances and the major degradation …

Analytical method development and validation of Alogliptin by RP-HPLC method

M Vinyas, S Velivela, G Yadav, NB Pati… - Research Journal of …, 2016 - indianjournals.com
A novel approach was used to develop and validate a rapid, specific, accurate and precise
reverse phase high performance liquid chromatographic (HPLC) method for the estimation …