Age-related macular degeneration: A two-level model hypothesis

MP Rozing, JA Durhuus, MK Nielsen, Y Subhi… - Progress in retinal and …, 2020 - Elsevier
Age-related diseases, including age-related macular degeneration (AMD), are of growing
importance in a world where population ageing has become a dominant global trend …

Dietary patterns, carbohydrates, and age-related eye diseases

SG Francisco, KM Smith, G Aragonès, EA Whitcomb… - Nutrients, 2020 - mdpi.com
Over a third of older adults in the US experience significant vision loss, which decreases
independence and is a biomarker of decreased health span. As the global aging population …

Development of macular atrophy in patients with wet age-related macular degeneration receiving anti-VEGF treatment

A Foss, T Rotsos, T Empeslidis, V Chong - Ophthalmologica, 2022 - karger.com
Age-related macular degeneration (AMD) is a leading cause of blindness. Late AMD can be
classified into exudative (commonly known as wet AMD [wAMD]) or dry AMD, both of which …

[HTML][HTML] Complement activation, lipid metabolism, and mitochondrial injury: Converging pathways in age-related macular degeneration

LX Tan, CJ Germer, N La Cunza, A Lakkaraju - Redox biology, 2020 - Elsevier
The retinal pigment epithelium (RPE) is the primary site of injury in non-neovascular age-
related macular degeneration or dry AMD. Polymorphisms in genes that regulate …

Association of lipid-lowering drugs and antidiabetic drugs with age-related macular degeneration: a meta-analysis in Europeans

MM Mauschitz, T Verzijden, AK Schuster… - British Journal of …, 2023 - bjo.bmj.com
Background/aims To investigate the association of commonly used systemic medications
with prevalent age-related macular degeneration (AMD) in the general population. Methods …

Shedding light on eye disease in obesity: A review

S Lam, J Lindsey, BG Carranza Leon… - Clinical …, 2024 - Wiley Online Library
Obesity is known to be associated with numerous ocular manifestations, including but not
limited to, diabetic retinopathy (DR), age‐related macular degeneration (AMD), cataracts …

Automated large-scale prediction of exudative AMD progression using Machine-Read OCT biomarkers

A Rudas, JN Chiang, G Corradetti, N Rakocz… - PLOS digital …, 2023 - journals.plos.org
Age-related Macular Degeneration (AMD) is a major cause of irreversible vision loss in
individuals over 55 years old in the United States. One of the late-stage manifestations of …

Preliminary investigation on simvastatin-loaded polymeric micelles in view of the treatment of the back of the eye

S Pescina, F Sonvico, A Clementino, C Padula, P Santi… - Pharmaceutics, 2021 - mdpi.com
There is increasing consensus in considering statins beneficial for age-related macular
degeneration and in general, for immune and inflammatory mediated diseases affecting the …

Soluble endoglin as a biomarker of successful rheopheresis treatment in patients with age-related macular degeneration

V Blaha, JU Rathouska, H Langrova, M Blaha… - Scientific Reports, 2024 - nature.com
Age-related macular degeneration (AMD) is a progressive chronic disease causing visual
impairment or central vision loss in the elderly. We hypothesized that successful …

Age‐related macular degeneration and myeloproliferative neoplasms–A common pathway

C Liisborg - 2022 - Wiley Online Library
Summary Dansk Resumé (Danish summary) Aldersrelateret makuladegeneration (AMD) er
den hyppigste årsag til uopretteligt synstab og blindhed i højindkomstlande. Det er en …