Diabetes mellitus has been recognised as one of the four major non-communicable
diseases that demands urgent attention from all key shareholders globally in an effort to …

Oxidative stress is a critical factor in the pathogenesis and progression of diabetes and its
associated complications. The imbalance between reactive oxygen species (ROS) …

The discovery that mammalian cells have the ability to synthesize the free radical nitric oxide
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …

Oxidative stress has been implicated in the pathophysiology of diabetic nephropathy.
Studies in experimental animal models of diabetes strongly implicate oxidant species as a …

The prevalence of diabetes has dramatically increased worldwide due to the vast increase
in the obesity rate. Diabetic nephropathy is one of the major complications of type 1 and type …

Diabetic nephropathy is a leading cause of end-stage renal failure worldwide. Its
morphologic characteristics include glomerular hypertrophy, basement membrane …

Pathophysiology of contrast medium–induced nephropathy. Background Contrast medium–
induced nephropathy (CIN) is a well-known cause of acute renal failure, but the …

At present, diabetic kidney disease affects about 15–25% of type 1 and 30–40% of type 2
diabetic patients. Several decades of extensive research has elucidated various pathways to …

Macro-and microvascular disease are the most common causes of morbidity and mortality in
patients with diabetes mellitus. Diabetic cardiovascular dysfunction represents a problem of …

In contrast with the short research history of the enzymatic synthesis of nitric oxide (NO), the
introduction of nitrate‐containing compounds for medicinal purposes marked its 150th …