Catheter-based renal denervation in patients with uncontrolled hypertension in the absence of antihypertensive medications (SPYRAL HTN-OFF MED): a randomised …

RR Townsend, F Mahfoud, DE Kandzari, K Kario… - The Lancet, 2017 - thelancet.com
Background Previous randomised renal denervation studies did not show consistent efficacy
in reducing blood pressure. The objective of our study was to evaluate the effect of renal …

Hypertension: history and development of established and novel treatments

M Wolf, S Ewen, F Mahfoud, M Boehm - Clinical Research in Cardiology, 2018 - Springer
Background This article summarizes the emerging field of hypertension over the last
decades. It covers paradigm shifts on hypertension from an undefined cardiovascular …

A multinational clinical approach to assessing the effectiveness of catheter-based ultrasound renal denervation: the RADIANCE-HTN and REQUIRE clinical study …

L Mauri, K Kario, J Basile, J Daemen, J Davies… - American heart …, 2018 - Elsevier
Catheter-based renal denervation is a new approach to treat hypertension via modulation of
the renal sympathetic nerves. Although nonrandomized and small, open-label randomized …

Renal denervation: is it ready for prime time?

L Lauder, MA Wolf, SS Scholz, M Hohl… - Current cardiology …, 2019 - Springer
Abstract Purpose of Review Interventional cardiology and in particular the field of renal
denervation is subject to constant change. This review provides an up to date overview of …

Renal denervation in comparison with intensified pharmacotherapy in true resistant hypertension: 2-year outcomes of randomized PRAGUE-15 study

J Rosa, P Widimský, P Waldauf, T Zelinka… - Journal of …, 2017 - journals.lww.com
Objectives: The randomized, multicentre study compared the efficacy of renal denervation
(RDN) versus spironolactone addition in patients with true resistant hypertension. We …

The addition of renal sympathetic denervation to pulmonary vein isolation reduces recurrence of paroxysmal atrial fibrillation in chronic kidney disease patients

MG Kiuchi, S Chen, GR e Silva… - Journal of Interventional …, 2017 - Springer
Background Atrial fibrillation (AF) frequently complicates chronic kidney disease (CKD). AF
treatment is challenging and requires complete pulmonary vein isolation (PVI). Recently …

Innervation of the developing kidney in vivo and in vitro

J Tarnick, M Elhendawi, I Holland, Z Chang… - Biology …, 2023 - journals.biologists.com
Within the adult kidney, renal neurites can be observed alongside the arteries where they
play a role in regulating blood flow. However, their role and localization during development …

Impact of renal denervation on tissue Na+ content in treatment-resistant hypertension

C Ott, C Kopp, A Dahlmann, A Schmid, P Linz… - Clinical Research in …, 2018 - Springer
Objectives Renal denervation (RDN) has been introduced for reducing blood pressure (BP)
in treatment-resistant hypertension (TRH). The precise mechanism how RDN exerts its BP …

Procedural and anatomical predictors of renal denervation efficacy using two radiofrequency renal denervation catheters in a porcine model

M Wolf, B Hubbard, A Sakaoka, S Rousselle… - Journal of …, 2018 - journals.lww.com
Methods: Domestic swine were assigned into two treatment groups (n= 10) and one sham
group (n= 3). Bilateral RDN in main and in branch segments of renal arteries was performed …

[HTML][HTML] Pulmonary vein isolation alone and combined with renal sympathetic denervation in chronic kidney disease patients with refractory atrial fibrillation

MG Kiuchi, S Chen, GR e Silva, LMR Paz… - Kidney research and …, 2016 - Elsevier
Background Atrial fibrillation (AF) commonly occurs in association with chronic kidney
disease (CKD), resulting in adverse outcomes. Combining pulmonary vein isolation (PVI) …