Vesicular approach of cubosomes, its components, preparation techniques, evaluation and their appraisal for targeting cancer cells

S Iqbal, M Zaman, MA Waqar, HS Sarwar… - Journal of Liposome …, 2024 - Taylor & Francis
Cancer has been characterized by abnormal and uncontrolled proliferation of cells. Majority
of drugs given through chemotherapy produce unwanted and adverse effects of …

Synthesis and characterization of chitosan-decorated nanoemulsion gel of 5-fluorouracil for topical delivery

A Nawaz, MS Latif, MA Alnuwaiser, S Ullah, M Iqbal… - Gels, 2022 - mdpi.com
(1) Background: The present study aimed to prepare chitosan-coated nanoemulsion gel
containing 5-fluorouracil for enhanced topical delivery.(2) Methods: To formulate the …

Preparation and characterization of patch loaded with clarithromycin nanovesicles for transdermal drug delivery

A Zaid Alkilani, B Musleh, R Hamed… - Journal of Functional …, 2023 - mdpi.com
Clarithromycin (CLR), categorized as a Biopharmaceutical Classification System class II
drug, has several gastrointestinal tract side effects and an extremely unpalatable bitter taste …

Formulation development and in vitro/in vivo characterization of methotrexate-loaded nanoemulsion gel formulations for enhanced topical delivery

MS Latif, A Nawaz, M Asmari, J Uddin, H Ullah… - Gels, 2022 - mdpi.com
Methotrexate-loaded oil-in-water nanoemulsion formulations were prepared using the high
shear homogenization technique. A drug excipient study (ATR-FTIR) was carried out to …

Formulation development and ex-vivo permeability of curcumin hydrogels under the influence of natural chemical enhancers

A Nawaz, A Farid, M Safdar, MS Latif, S Ghazanfar… - Gels, 2022 - mdpi.com
Background: The aim of the present research was to formulate and evaluate curcumin
hydrogel and to investigate the potential of natural essential oils as permeation enhancers …

Synthesis and evaluation of poly (3-hydroxypropyl ethylene-imine) and its blends with chitosan forming novel elastic films for delivery of haloperidol

S Soradech, P Kengkwasingh, AC Williams… - Pharmaceutics, 2022 - mdpi.com
This study aimed to develop novel elastic films based on chitosan and poly (3-hydroxypropyl
ethyleneimine) or P3HPEI for the rapid delivery of haloperidol. P3HPEI was synthesized …

Preparation and in vitro evaluation of controlled-release matrices of losartan potassium using ethocel grade 10 and carbopol 934P NF as rate-controlling polymers

KA Khan, C Zizzadoro, A Di Cerbo, N Pugliese… - Polymers, 2022 - mdpi.com
Controlled-release formulations are essential for those drugs that require fine tuning of their
activity to increase the ratio between therapeutic vs. adverse effects. Losartan potassium is …

Pharmacodynamic Studies of Pravastatin Sodium Nanoemulsion Loaded Transdermal Patch for Treatment of Hyperlipidemia

SI Elsayed, MS El-Dahan, GNS Girgis - AAPS PharmSciTech, 2024 - Springer
Pravastatin sodium (PVS) is a hypolipidemic drug with poor oral bioavailability due to the
first-pass effect. Therefore, this study aims to formulate and evaluate transdermal patches …

Fabrication of polymeric hydrogels containing esomeprazole for oral delivery: In vitro and in vivo pharmacokinetic characterization

I Ullah, AS Farooq, I Naz, W Ahmad, H Ullah, S Sehar… - Polymers, 2023 - mdpi.com
Hydrogel is one of the most interesting and excellent candidates for oral drug delivery. The
current study focuses on formulation development of hydrogels for controlled oral delivery of …

Formulation and characterization of ethyl cellulose-based patches containing curcumin-chitosan nanoparticles for the possible management of inflammation via skin …

A Nawaz, MS Latif, MKA Shah, TM Elsayed, S Ahmad… - Gels, 2023 - mdpi.com
Curcumin, a natural phenolic compound, exhibits poor absorption and extensive first pass
metabolism after oral administration. In the present study, curcumin-chitosan nanoparticles …